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H0501

Sigma-Aldrich

DL-Homocystine

≥98% (TLC)

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Synonym(s):
meso-4,4′-Dithio-bis(2-aminobutanoic acid)
Linear Formula:
HOOCCH(NH2)CH2CH2SSCH2CH2CH(NH2)COOH
CAS Number:
870-93-9
Molecular Weight:
268.35
Beilstein:
1728581
EC Number:
212-803-5
MDL number:
MFCD00069587
UNSPSC Code:
12352209
eCl@ss:
42021308
PubChem Substance ID:
24895403
NACRES:
NA.26

Assay

≥98% (TLC)

Quality Level

200

form

powder

color

white to off-white

mp

>300 °C

application(s)

detection

SMILES string

N[C@H](CCSSCC[C@H](N)C(O)=O)C(O)=O

InChI

1S/C8H16N2O4S2/c9-5(7(11)12)1-3-15-16-4-2-6(10)8(13)14/h5-6H,1-4,9-10H2,(H,11,12)(H,13,14)/t5-,6+

InChI key

ZTVZLYBCZNMWCF-OLQVQODUSA-N

Gene Information

human ... BHMT(635)

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Related Categories

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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K Yokoi et al.
The Journal of nutrition, 131(4), 1302-1308 (2001-04-04)
The effect of dietary sulfur amino acids on bioelectric properties was studied in rats by using bioimpedance spectroscopy. Weanling rats were assigned to one of 12 groups in a factorially arranged experiment with dietary variables of supplemental sulfur amino acid
Sezgin Bakirdere et al.
Analytica chimica acta, 680(1-2), 41-47 (2010-10-26)
An analytical method was developed for the determination of thiols in biological samples. Reverse phase chromatography coupled to ICP quadrupole MS or Orbitrap MS was employed for the separation and detection of thiols. For the determination of total thiols, oxidized
Lei Li et al.
Amino acids, 50(10), 1485-1494 (2018-08-01)
Plasma homocysteine is elevated in patients with impaired renal function, and markedly so at end-stage renal disease. As chronic kidney disease and hyperhomocysteinemia are also independent risk factors for cardiovascular disease, the latter is hypothesized to accelerate vascular abnormalities following
Jason L Robinson et al.
Amino acids, 48(12), 2821-2830 (2016-08-27)
Methionine metabolism is critical during development with significant requirements for protein synthesis and transmethylation reactions. However, separate requirements of methionine for protein synthesis and transmethylation are difficult to define because after transmethylation, demethylated methionine is either irreversibly oxidized to cysteine
Valeria Angeli et al.
Talanta, 82(2), 815-820 (2010-07-07)
Chromatographic determination of glutathione disulfide (GSSG) without any preliminary reduction has been presented using GSSG derivatization by p-hydroxymercuribenzoate (pHMB) in strong alkaline medium followed by the determination of GS-pHMB complex by reversed phase chromatography coupled to chemical vapour generation and
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