GW20080F
Anti-Haptoglobin antibody produced in chicken
affinity isolated antibody, buffered aqueous solution
Synonym(s):
Anti-MGC111141
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About This Item
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA (i), WB
Citations:
4
biological source
chicken
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
human, rat, mouse
manufacturer/tradename
Genway 15-288-20080F
technique(s)
indirect ELISA: suitable, western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... HP(3240)
Application
Anti-Haptoglobin antibody produced in chicken is suitable for indirect ELISA and western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
Biochem/physiol Actions
Haptoglobin (abbreviated as Hp) is the protein encoded by the HP gene in humans. It is an "acute phase" protein that has different functions displaying genetic polymorphism and has are 3 major phenotypes. Haptoglobin is capable of binding haemoglobin, there by preventing iron loss and renal damage. The complex of haptoglobin with haemoglobin is metabolized in the heptic reticuloendothelial system and it occurs in the liver, adipose tissue and in lung. It acts as an antioxidant and has antibacterial activity. Haptoglobin plays an important role in modulating many aspects of the acute phase response.
Physical form
Solution in phosphate buffered saline containing 0.02% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
Regulatory Information
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Takumi Konno et al.
Biochemical and biophysical research communications, 638, 127-133 (2022-11-30)
Zonulin is a physiologic epithelial and endothelial permeability modulator. Zonulin increases antigen trafficking from the gut lumen into the bloodstream and in between body compartments, a mechanism linked to many chronic inflammatory diseases. Upon its initial discovery, it was noted
J Wassell
Clinical laboratory, 46(11-12), 547-552 (2000-12-08)
Haptoglobin is an acute phase protein capable of binding haemoglobin, thus preventing iron loss and renal damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. There
W Dobryszycka
European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies, 35(9), 647-654 (1997-11-14)
Haptoglobin, an "acute phase" protein, has different functions, which display genetic polymorphism. The complex of haptoglobin with haemoglobin is metabolized in the heptic reticuloendothelial system. Biosynthesis of haptoglobin occurs not only in the liver, but also in adipose tissue and
Enid E Martinez et al.
Scientific reports, 11(1), 22462-22462 (2021-11-19)
We examined the relationship between zonulin and gastric motility in critical care patients and a translational mouse model of systemic inflammation. Gastric motility and haptoglobin (HP) 2 isoform quantification, proxy for zonulin, were examined in patients. Inflammation was triggered by
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