SeraSil-Mag 700 silica coated superparamagnetic beads

SeraSil-Mag silica coated superparamagnetic beads for nucleic acid isolation deliver high purity DNA extraction for highly sensitive applications where sample is scarce. These beads provide an optimal surface for nucleic acid binding with high performance and low background. For ongoing reliability, SeraSil-Mag is supported by Cytiva′s expertise in Sera-Mag bead technology and commitment to quality standards.

• High magnetization (60 emu/g) and strong binding capacity giving fast magnetic response (~5 secs) and shorten time required for magnetic steps during isolation.
• Beads come in two sizes (submicroscale diameter 700 nm and 400 nm), offering choice based on surface requirements and high binding capacity due to the small sized particles.
• Beads are monodispersed with narrow size distribution for consistent, reproducible results.
• Silanol hydroxyl groups on the bead surface give efficient, high purity isolation of nucleic acids.
• Tested for microbial contamination.
• Good buoyancy stability (low sedimentation rate): beads remain well suspended and dispersed for over 90 mins (at 1 mg/mL concentration),* providing good handling and suitability for automation. *Beads may settle faster at higher concentration.
• SeraSil-Mag beads are compatible with chaotropic salt chemistry and vortex mixing, roller mixing and sonication.

Tightly controlled production processes result in core-shell beads which are uniform and spherical. The silica shell provides a high content of silanol surface groups and encloses the magnetic core. The submicron size allows for a high surface area and abundant binding sites. The narrow particle size distribution assures uniformity and consistency of the beads.

The magnetic nanoparticles within the core provide superparamagnetic properties to the SeraSil-Mag beads, resulting in extremely fast magnetic separation in the presence of a magnet. There is no residual magnetization when the magnetic field is removed, which further contributes to ease of handling during use.