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Dear Customer:

The current international situation is complex and volatile, and uncertain tariff policies may potentially impact our product prices. Given these uncertainties, we value your understanding regarding order-related matters.

If you decide to place an order during this period, we reserve the right to adjust the price based on the evolving situation. We understand that market changes may cause inconvenience. We will negotiate with you if there’s a significant price fluctuation due to tariff policy changes before the order’s actual delivery, and in such cases we may adjust or cancel the order as necessary.

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Key Documents

Safety Information

GE17549852

HiTrap® MabSelect PrismA

Cytiva, 17549852, pack of 5 × 1 mL

Synonym(s):

MabSelect PrismA

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About This Item

UNSPSC Code:
41106500
NACRES:
NB.21

Product GE17549852 is not currently sold in your country. Contact Technical Service

packaging

pack of 5 × 1 mL

manufacturer/tradename

17549852
Cytiva

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GE17549851GE17549853GE17549111
packaging

pack of 5 × 1 mL

packaging

pack of 1 × 1 mL

packaging

pack of 1 × 5 mL

packaging

pkg of 5 × 1 mL

General description

These HiTrap columns are prepacked with MabSelect PrismA protein A chromatography resin. This affinity resin in the packed column has been improved with an optimized high-flow agarose base matrix and a genetically engineered protein ligand, allowing efficient cleaning between monoclonal antibody purification runs. This allows future demands in monoclonal antibody purification to be met, including processing of many bispecific antibodies.

The enhanced alkaline stability of MabSelect PrismA also provides opportunities for more robust mAb purification using periodic counter-current chromatography. The possibility for cleaning using 1 M NaOH increases bioburden control for continuous processes, which can be exposed to days or weeks of feed harvest.

Features and Benefits

  • Enhanced binding capacity compared with other Protein A resins
  • Excellent alkaline stability enables efficient cleaning and sanitization using 0.5–1.0 M NaOH
  • Covered by a comprehensive security of supply program, including dual sources of the agarose base matrix and protein A ligand.
  • The PrismA protein A ligand is also available in HiTrap® Fibro and HiScreen Fibro PrismA chromatography units for ultrafast purification of mAbs.
  • Easily measure protein A leakage using the PrismA ELISA kit specifically designed for use with MabSelect PrismA resins.

Legal Information

HiScreen is a trademark of Cytiva
HiTrap is a registered trademark of Cytiva
MabSelect is a trademark of Cytiva

Pictograms

Flame

Signal Word

Danger

Hazard Statements

Hazard Classifications

Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

55.4 °F

Flash Point(C)

13 °C

Regulatory Information

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    Related Content

    Purification methods for downstream analysis reduce sample complexity, remove interferences, and concentrate analytes for more accurate results.

    Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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