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About This Item
NACRES:
NB.21
UNSPSC Code:
41106500
packaging
pack of 5 × 1 mL
manufacturer/tradename
17549852, Cytiva
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General description
These HiTrap columns are prepacked with MabSelect PrismA protein A chromatography resin. This affinity resin in the packed column has been improved with an optimized high-flow agarose base matrix and a genetically engineered protein ligand, allowing efficient cleaning between monoclonal antibody purification runs. This allows future demands in monoclonal antibody purification to be met, including processing of many bispecific antibodies.
The enhanced alkaline stability of MabSelect PrismA also provides opportunities for more robust mAb purification using periodic counter-current chromatography. The possibility for cleaning using 1 M NaOH increases bioburden control for continuous processes, which can be exposed to days or weeks of feed harvest.
The enhanced alkaline stability of MabSelect PrismA also provides opportunities for more robust mAb purification using periodic counter-current chromatography. The possibility for cleaning using 1 M NaOH increases bioburden control for continuous processes, which can be exposed to days or weeks of feed harvest.
Features and Benefits
- Enhanced binding capacity compared with other Protein A resins
- Excellent alkaline stability enables efficient cleaning and sanitization using 0.5–1.0 M NaOH
- Covered by a comprehensive security of supply program, including dual sources of the agarose base matrix and protein A ligand.
- The PrismA protein A ligand is also available in HiTrap® Fibro and HiScreen™ Fibro PrismA chromatography units for ultrafast purification of mAbs.
- Easily measure protein A leakage using the PrismA ELISA kit specifically designed for use with MabSelect™ PrismA resins.
Legal Information
MabSelect is a trademark of Cytiva
HiScreen is a trademark of Cytiva
HiTrap is a registered trademark of Cytiva
signalword
Danger
hcodes
Hazard Classifications
Flam. Liq. 2
Storage Class
3 - Flammable liquids
wgk
WGK 1
flash_point_f
55.4 °F
flash_point_c
13 °C
Regulatory Information
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在分析之前，可以应用多种化学和物理纯化方法分离或浓缩目标分析物，有助于将样品制成与分析技术相兼容的形式，降低样品复杂性，去除干扰杂质，并在分析之前浓缩分析物。
Purification methods for downstream analysis reduce sample complexity, remove interferences, and concentrate analytes for more accurate results.
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