GE17-5269-02
MabSelect™ Xtra
Cytiva 17-5269-02, pack of 200 mL
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ligand
recombinant protein A (E. coli)
shelf life
Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service.
packaging
pack of 200 mL
manufacturer/tradename
Cytiva 17-5269-02
storage condition
(20% Ehtanol)
matrix
highly cross-linked agarose
avg. part. size
75 (d₅₀v is the median particle size of the cumulative volume distribution)
cleaning in place
2-12(pH below 3 is sometimes required to elute strongly bound IgG species. However, protein ligands may hydrolyze at very low pH.)
working range
3-10(pH below 3 is sometimes required to elute strongly bound IgG species. However, protein ligands may hydrolyze at very low pH.)
capacity
≥30 mg binding capacity (humanlgG/ml at 2.4 min residence time)(Determined at 10% breakthrough by frontal analysis at a mobile phase velocity of 500 cm/h in a column with a bed height of 20 cm.)
suitability
suitable for bioprocess medium
storage temp.
2-8°C
General description
Application
The medium provides a lower overall production cost due to the possibility of processing concentrated feedstocks in fewer batches.
MabSelect™ Xtra is available in a range of different bulk pack sizes and convenient pre-packed formats for easy scale-up and process development. As member of the BioProcess media range, MabSelect™ Xtra meets industrial demands with security of supply and comprehensive technical and regulatory support.
Features and Benefits
- Higher dynamic binding capacity than currently available Protein A chromatography media.
- Improved process economics through reduced raw materials costs and/or reduced number of cycles
- High purity capture due to high ligand selectivity and matrix hydrophilicity
- Slightly lower pressure/fLow properties compared to MabSelect™ SuRe™ and MabSelect
Analysis Note
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Signal Word
Warning
Hazard Statements
Precautionary Statements
Regulatory Information
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Articles
This page describes efficient column packing and preparation for affinity chromatography of antibodies.
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Purification methods for downstream analysis reduce sample complexity, remove interferences, and concentrate analytes for more accurate results.
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