G9885
α1-Acid Glycoprotein from human plasma
≥99% (agarose gel electrophoresis)
Sign Into View Organizational & Contract Pricing
All Photos(3)
Synonym(s):
AGP, Orosomucoid
Recommended Products
biological source
human plasma
Quality Level
Assay
≥99% (agarose gel electrophoresis)
form
powder
technique(s)
ELISA: suitable
impurities
HIV-1/HIV-2, HCV and hepatitis B antigen, tested negative
UniProt accession no.
storage temp.
2-8°C
Gene Information
human ... ORM1(5004)
Looking for similar products? Visit Product Comparison Guide
Related Categories
General description
α-1-Acid glycoprotein (AGP)/orosomucoid (ORM), a glycoprotein has a molecular weight of 41-43kDa. It is considered as one of the important acute phase proteins in humans and rats. AGP may belong to the lipocalin family.
Application
α1-Acid glycoprotein from human plasma has been used:
- as negatively charged protein to investigate the adsorption processes onto the surface of polyelectrolyte multilayers
- to incubate plates coated with purified antiserum in the study to investigate its serum concentration by ELISA
- to study the effect of its different concentrations on the antiviral activity of human immunodeficiency virus (HIV) protease inhibitors
Biochem/physiol Actions
α1-Acid glycoprotein possesses immunomodulating effects. It has the ability to bind to acidic drugs, like phenobarbital.
Preparation Note
Purified from Cohn Fraction VI
Disclaimer
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
常规特殊物品
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
In Vitro Effect of alpha1-Acid Glycoprotein on the Anti?Human Immunodeficiency Virus (HIV) Activity of the Protease Inhibitor CGP 61755: A Comparative Study with Other Relevant HIV Protease Inhibitors
Lazdins J K, et al.
The Journal of Infectious Diseases, 175(5), 1063-1070 (1997)
Hendrik Grootaert et al.
Glycobiology, 30(9), 735-745 (2020-03-10)
The deoxy sugar l-fucose is frequently found as a glycan constituent on and outside living cells, and in mammals it is involved in a wide range of biological processes including leukocyte trafficking, histo-blood group antigenicity and antibody effector functions. The
Chenhua Zhang et al.
Analytica chimica acta, 1078, 189-199 (2019-07-31)
Silica-based lectin microcolumns were developed and optimized for the separation and analysis of glycoform fractions in alpha1-acid glycoprotein (AGP) based on both the degree of branching and level of fucosylation. Concanavalin A (Con A) and Aleuria Aurantia lectin (AAL) were
Jae Woong Choi et al.
Journal of microbiology and biotechnology, 30(9), 1297-1304 (2020-07-07)
Elevated serum levels of alpha-1-acid glycoprotein (AGP) are known to be associated with several types of cancer. In addition, some reports have indicated that changes in glycosylation of AGP are associated with cancer progression. However, changes in AGP levels of
Alpha-1-acid glycoprotein
Fournier T, et al.
Biochimica et Biophysica Acta, 1482(1-2), 157-171 (2000)
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service