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G8876

Sigma-Aldrich

Glycogen from rabbit liver

≥85% dry basis (enzymatic)

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CAS Number:
9005-79-2
EC Number:
232-683-8
MDL number:
MFCD00081547
UNSPSC Code:
12352201
NACRES:
NA.25

biological source

rabbit liver

Quality Level

200

Assay

≥85% dry basis (enzymatic)

form

powder

color

white to off-white

solubility

water: 40 mg/mL, clear to turbid, colorless to light yellow

storage temp.

2-8°C

InChI

1S/C24H42O21/c25-1-5-9(28)11(30)16(35)22(41-5)39-4-8-20(45-23-17(36)12(31)10(29)6(2-26)42-23)14(33)18(37)24(43-8)44-19-7(3-27)40-21(38)15(34)13(19)32/h5-38H,1-4H2/t5-,6-,7-,8-,9-,10-,11+,12+,13-,14-,15-,16-,17-,18-,19-,20-,21+,22+,23-,24-/m1/s1

InChI key

BYSGBSNPRWKUQH-UJDJLXLFSA-N

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General description

Glycogen is a branched polymer of glucose synthesized by animal cells for energy storage and release. It is constructed of predominantly α1→4 glycosidic bonds with branches created through α1→6 glycosidic bonds.

Application

  • Glycogen from rabbit liver has been use as a standard for measurement of the hepatic glycogen content.
  • In the1,4-α-D gIucan:orthophosphate α-glucosyl transferase assay, it has been used in the assay mixture.
  • It has also been used as a standard for myocardial tissue glycogen analysis.

Biochem/physiol Actions

Glycogen from rabbit liver helps in maintaining blood glucose levels by regulating the release of glucose in between meals. It also provides energy during sudden, strenuous activity. Two important areas of glycogen storage are the liver and skeletal muscle.

Preparation Note

Prepared by a modification of the procedure of Bell, et al., Biochem. J., 28, 882 (1934).

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Relationship between beta-adrenergic receptor numbers and physiological responses during experimental canine myocardial ischemia.
Mukherjee A, et al.
Circulation Research, 50, 735-741 (1982)
Daily rhythms in metabolic liver enzymes and plasma glucose require a balance in the autonomic output to the liver.
Cailotto C, et al.
Endocrinology, 149, 1914-1925 (2008)
Glycogen Metabolism
Berg JM, et al.
Biochemistry (2002)
M A Brooks et al.
Poultry science, 95(5), 1096-1104 (2016-03-05)
The objective of this study was to evaluate the effects of dietary chromium (Cr), as chromium propionate, on measures of insulin sensitivity. Liver and muscle glycogen, and plasma glucose and non-esterified fatty acid (NEFA) concentrations were used as indicators of
Developmental changes in ovine myocardial glucose transporters and insulin signaling following hyperthermia-induced intrauterine fetal growth restriction.
Barry JS, et al.
Experimental Biology and Medicine (Maywood, N.J.), 231, 566-575 (2006)
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