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G7000

Sigma-Aldrich

α-D-Glucose 1-phosphate disodium salt hydrate

≥97% (Enzymatic Purity, anhydrous)

Synonym(s):

α-D-Glucopyranose 1-phosphate, Cori ester

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About This Item

Linear Formula:
C6H11O9PNa2 · xH2O
CAS Number:
56401-20-8
Molecular Weight:
304.10 (anhydrous basis)
EC Number:
260-154-1
MDL number:
MFCD00150837
UNSPSC Code:
12352201
PubChem Substance ID:
24895281
NACRES:
NA.25

biological source

synthetic

Quality Level

200

Assay

≥97% (Enzymatic Purity, anhydrous)

form

powder

impurities

≤0.1 mol % glucose
≤0.5 mol % α-D-glucose 1,6-diphosphate

color

white

solubility

water: 50 mg/mL, clear, colorless

cation traces

Na: 13.5-16.7% (anhydrous)

application(s)

agriculture

storage temp.

−20°C

SMILES string

[Na+].[Na+].[H]O[H].OC[C@H]1O[C@H](OP([O-])([O-])=O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C6H13O9P.2Na.H2O/c7-1-2-3(8)4(9)5(10)6(14-2)15-16(11,12)13;;;/h2-10H,1H2,(H2,11,12,13);;;1H2/q;2*+1;/p-2/t2-,3-,4+,5-,6-;;;/m1.../s1

InChI key

YWAUQXHOCBBYLP-FBNUBEQJSA-L

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General description

α-D-Glucose 1-phosphate is converted into D-glucose-6-phosphate by the enzyme phosphoglucomutase.

Biochem/physiol Actions

Glucose-1-phosphate (G1P) is produced from glycogen during glycogenolysis by the actions of glycogen phosphorylase. Conversion to glucose-6-phosphate (G6P) by phosphoglucomutase allows for entry of the glucose molecule into metabolic pathways such as glycolysis. During glycogenesis, G6P is converted to G1P by the actions of phosphoglucose isomerase.

Preparation Note

Prepared by a modification of the procedure of McCready, R.M., et al., J. Am. Chem. Soc., 66, 560 (1944).

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

监管及禁止进口产品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Rickard Olsson et al.
Environmental science & technology, 46(1), 285-291 (2011-11-23)
Esters of phosphoric acid constitute a sizable fraction of the total phosphorus supply in the environment and thus play an important role in the global phosphorus cycle. Enzymatic hydrolysis of these esters to produce orthophosphate is often a required reaction
Fumiaki Ito et al.
Biochimica et biophysica acta, 1844(4), 759-766 (2014-02-05)
The archaeal non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (GAPN, EC 1.2.1.9) is a highly allosteric enzyme activated by glucose 1-phosphate (Glc1P). Recent kinetic analyses of two GAPN homologs from Sulfolobales show different allosteric behaviors toward the substrate glyceraldehyde-3-phosphate (GAP) and the allosteric effector
Xingwei Chen et al.
Journal of biomaterials applications, 27(4), 391-402 (2011-07-14)
The purpose of this study was to evaluate the feasibility of in situ thermosensitive hydrogel based on chitosan in combination with disodium α-d-Glucose 1-phosphate (DGP) for ocular drug delivery system. Aqueous solution of chitosan/DGP underwent sol-gel transition as temperature increased
Rickard Olsson et al.
Langmuir : the ACS journal of surfaces and colloids, 26(24), 18760-18770 (2010-11-20)
Adsorption, desorption, and precipitation reactions at environmental interfaces govern the fate of phosphorus in terrestrial and aquatic environments. Typically, a substantial part of the total pool of phosphorus consists of organophosphate, and in this study we have focused on the
Joerg Fettke et al.
Plant physiology, 155(4), 1723-1734 (2010-12-01)
Almost all glucosyl transfer reactions rely on glucose-1-phosphate (Glc-1-P) that either immediately acts as glucosyl donor or as substrate for the synthesis of the more widely used Glc dinucleotides, ADPglucose or UDPglucose. In this communication, we have analyzed two Glc-1-P-related
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