G6014
rac-Glycerol 1-phosphate disodium salt hydrate
≥75% (enzymatic)
Synonym(s):
DL-α-Glycerophosphate disodium salt hydrate
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About This Item
Empirical Formula (Hill Notation):
C3H7Na2O6P · xH2O
CAS Number:
Molecular Weight:
216.04 (anhydrous basis)
PubChem Substance ID:
UNSPSC Code:
12352201
Beilstein/REAXYS Number:
5177716
MDL number:
SMILES string
O.[Na+].[Na+].OCC(O)COP([O-])([O-])=O
InChI
1S/C3H9O6P.2Na.H2O/c4-1-3(5)2-9-10(6,7)8;;;/h3-5H,1-2H2,(H2,6,7,8);;;1H2/q;2*+1;/p-2
InChI key
OFNNKPAERNWEDD-UHFFFAOYSA-L
assay
≥75% (enzymatic)
impurities
~6 mol/mol water
storage temp.
2-8°C
Application
rac-Glycerol 1-phosphate does not affect the growth and metabolism of E. coli at concentrations of 5-100μm.
Biochem/physiol Actions
rac-Glycerol 1-phosphate was shown to be produced in mammalian tissues by the hydrolysis of rac-glycerol 1:2-cyclic phosphate by a soluble phosphodiesterase.
Analysis Note
The main impurity is β-glycerophosphate.
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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Kyung Ok Yu et al.
Biotechnology and bioengineering, 110(1), 343-347 (2012-08-14)
Triacylglycerol (TAG) is a microbial oil feedstock for biodiesel production that uses an inexpensive substrate, such as glycerol. Here, we demonstrated the overproduction of TAG from glycerol in engineered Saccharomyces cerevisiae via the glycerol-3-phosphate (G3P) pathway by overexpressing the major
Jiangwei Yao et al.
Biochimica et biophysica acta, 1831(3), 495-502 (2012-09-18)
Membrane phospholipid synthesis is a vital facet of bacterial physiology. Although the spectrum of phospholipid headgroup structures produced by bacteria is large, the key precursor to all of these molecules is phosphatidic acid (PtdOH). Glycerol-3-phosphate derived from the glycolysis via
Adam L Orr et al.
The Journal of biological chemistry, 287(51), 42921-42935 (2012-11-06)
The oxidation of sn-glycerol 3-phosphate by mitochondrial sn-glycerol 3-phosphate dehydrogenase (mGPDH) is a major pathway for transfer of cytosolic reducing equivalents to the mitochondrial electron transport chain. It is known to generate H(2)O(2) at a range of rates and from
Sanjeewa Gamagedara et al.
Bioanalysis, 4(10), 1175-1183 (2012-06-02)
Urinary metabolomic profiles have recently drawn a lot of attention owing to a debate regarding their possible role as potential clinical markers for prostate cancer. In this study, levels of proline, kynurenine, uracil and glycerol-3-phosphate in 126 patients with genitourinary
Haruo Shimada et al.
Biochemistry, 50(19), 4114-4120 (2011-04-09)
The structure of membrane lipids in Archaea is different from those of Bacteria and Eucarya in many ways including the chirality of the glycerol backbone. Until now, heterochiral membranes were believed to be unstable; thus, no cellular organism could have
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