Key Documents

View All Documentation

G6013

L-Glutathione reduced

Name: <SC>L</SC>-Glutathione reduced
Brand: SIGMA

≥98.0%, suitable for cell culture, BioReagent

Synonym(s):

Glutathione, Reduced, γ-L-Glutamyl-L-cysteinyl-glycine, GSH

Select a Size

Change View

About This Item

Linear Formula:

H₂NCH(CO₂H)CH₂CH₂CONHCH(CH₂SH)CONHCH₂CO₂H

CAS Number:

70-18-8

Molecular Weight:

307.32

NACRES:

NA.26

PubChem Substance ID:

24895241

UNSPSC Code:

12352209

EC Number:

200-725-4

MDL number:

MFCD00065939

Beilstein/REAXYS Number:

1729812

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

Product Name

L-Glutathione reduced, suitable for cell culture, BioReagent, ≥98.0%, powder

product line

BioReagent

Quality Level

300

assay

≥98.0%

form

powder

technique(s)

cell culture | mammalian: suitable

color

white

mp

192-195 °C (dec.) (lit.)

solubility

H₂O: 50 mg/mL

storage temp.

2-8°C

SMILES string

N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O

InChI

1S/C10H17N3O6S/c11-5(10(18)19)1-2-7(14)13-6(4-20)9(17)12-3-8(15)16/h5-6,20H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)/t5-,6-/m0/s1

InChI key

RWSXRVCMGQZWBV-WDSKDSINSA-N

Description

Application

May be used at 5-10 mM to elute glutathione S-transferase (GST) from glutathione agarose.

Biochem/physiol Actions

Endogenous antioxidant that plays a major role in reducing reactive oxygen species formed during cellular metabolism and the respiratory burst. Glutathione-S-transferase catalyzes the formation of glutathione thioethers with xenobiotics, leukotrienes, and other molecules that have an electrophilic center. Glutathione also forms disulfide bonds with cysteine residues in proteins. Via these mechanisms, it can have the paradoxical effect of reducing the efficacy of anti-cancer agents.

Still not finding the right product?

Explore all of our products under L-Glutathione reduced

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Articles

Dietary Antioxidants

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

Glutathione in Cell Culture

Learn how glutathione and other components affect serum-free cell culture systems for protein biomanufacturing.

Amino Acid Codon Wheel

Amino Acid Codon Wheel for fast RNA translation. Find which amino acid is translated from your RNA sequence quickly and easily.

View All Articles

The AVR2-SIX5 gene pair is required to activate I-2-mediated immunity in tomato.

Lisong Ma et al.

The New phytologist, 208(2), 507-518 (2015-05-15)

Plant-invading microbes betray their presence to a plant by exposure of antigenic molecules such as small, secreted proteins called 'effectors'. In Fusarium oxysporum f. sp. lycopersici (Fol) we identified a pair of effector gene candidates, AVR2-SIX5, whose expression is controlled

Adseverin plays a role in osteoclast differentiation and periodontal disease-mediated bone loss.

Hongwei Jiang et al.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 29(6), 2281-2291 (2015-02-15)

Osteoclast differentiation and function are highly dependent on the assembly and turnover of actin filaments, but little is known about the roles of actin binding proteins in these processes. Adseverin (Ads), a member of the gelsolin superfamily of actin capping

Ligand-directed tosyl chemistry for protein labeling in vivo.

Shinya Tsukiji et al.

Nature chemical biology, 5(5), 341-343 (2009-03-31)

Here we describe a method for the site-selective attachment of synthetic molecules into specific 'endogenous' proteins in vivo using ligand-directed tosyl (LDT) chemistry. This approach was applied not only for chemically labeling proteins in living cells, tissues and mice but

View All Related Papers

Global Trade Item Number

SKU	GTIN
G6013-25G	04061833638743
G6013-100G	04061833611098
G6013-5G	04061833638750
G6013-10G	04061833638736