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Merck
CN

G5923

[8]-Gingerol

Synonym(s):

(S)-5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-dodecanone, 8-Gingerol

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About This Item

Empirical Formula (Hill Notation):
C19H30O4
CAS Number:
23513-08-8
Molecular Weight:
322.44
UNSPSC Code:
12352205
NACRES:
NA.25
PubChem Substance ID:
329799947
MDL number:
MFCD00877794
Beilstein/REAXYS Number:
2059802

Key Documents

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InChI key

BCIWKKMTBRYQJU-INIZCTEOSA-N

SMILES string

CCCCCCC[C@H](O)CC(=O)CCc1ccc(O)c(OC)c1

InChI

1S/C19H30O4/c1-3-4-5-6-7-8-16(20)14-17(21)11-9-15-10-12-18(22)19(13-15)23-2/h10,12-13,16,20,22H,3-9,11,14H2,1-2H3/t16-/m0/s1

color

white to yellow

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

−20°C

Quality Level

200

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Related Categories

Biochem/physiol Actions

[8]-Gingerol is a bioactive compound found in ginger (Zingiber officinale) with anti-inflammatory and antioxidant activity.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
0000137582
0000116054
0000116053
SLCD6605
079M4771V

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Andreas Nievergelt et al.
Bioorganic & medicinal chemistry, 18(9), 3345-3351 (2010-04-07)
Animal studies suggest that ginger (Zingiber officinale Roscoe) reduces anxiety. In this study, bioactivity-guided fractionation of a ginger extract identified nine compounds that interact with the human serotonin 5-HT(1A) receptor with significant to moderate binding affinities (K(i)=3-20 microM). [(35)S]-GTP gamma
Zhufeng Wu et al.
The Journal of pharmacy and pharmacology, 67(4), 583-596 (2014-12-17)
To determine the reaction kinetics for regioselective glucuronidation of gingerols (i.e. 6-, 8- and 10-gingerol) by human liver microsomes and expressed UDP-glucuronosyltransferase (UGT) enzymes, and to identify the main UGT enzymes involved in regioselective glucuronidation of gingerols. The rates of
Wen Xu et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 986-987, 69-84 (2015-02-25)
Gua-Lou-Gui-Zhi decoction (GLGZD) is a classical formula of traditional Chinese medicine, which has been commonly used to treat dysfunction after stroke, epilepsy and spinal cord injury. In this study, a systematic method was established for chemical profiling and quantification analysis

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