Skip to Content
Merck
CN
All Photos(1)

Documents

G5793

Sigma-Aldrich

GR 127935 hydrochloride hydrate

>98% (HPLC), powder

Synonym(s):

N-[4-Methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2´-methyl-4´-(5-methyl-1,2,4-oxadiazol-3-yl)-1,1´-biphenyl-4-carboxamide hydrochloride hydrate

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C29H31N5O3 · HCl · xH2O
CAS Number:
148642-42-6
Molecular Weight:
534.05 (anhydrous basis)
MDL number:
MFCD11045922
UNSPSC Code:
12352200
PubChem Substance ID:
24278688
NACRES:
NA.77

Quality Level

100

Assay

>98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

DMSO: 10 mg/mL, clear

originator

GlaxoSmithKline

storage temp.

2-8°C

SMILES string

O.Cl.COc1ccc(NC(=O)c2ccc(cc2)-c3ccc(cc3C)-c4noc(C)n4)cc1N5CCN(C)CC5

InChI

1S/C29H31N5O3.ClH.H2O/c1-19-17-23(28-30-20(2)37-32-28)9-11-25(19)21-5-7-22(8-6-21)29(35)31-24-10-12-27(36-4)26(18-24)34-15-13-33(3)14-16-34;;/h5-12,17-18H,13-16H2,1-4H3,(H,31,35);1H;1H2

InChI key

KSXUSAQPMSACQS-UHFFFAOYSA-N

Gene Information

human ... HTR1B(3351) , HTR1D(3352)

Biochem/physiol Actions

Potent, selective and orally active 5-HT1B/1D serotonin receptor antagonist.

Features and Benefits

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Caution

Desiccate

Legal Information

Sold for research purposes under agreement from Glaxo­Smith­Kline

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service