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G5146

Sigma-Aldrich

D-(+)-Glucose

Hybri-Max™, powder, BioReagent, suitable for hybridoma

Synonym(s):

Dextrose

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About This Item

Empirical Formula (Hill Notation):
C6H12O6
CAS Number:
50-99-7
Molecular Weight:
180.16
Beilstein:
1724615
EC Number:
200-075-1
MDL number:
MFCD00063774
UNSPSC Code:
12352201
PubChem Substance ID:
24895199
NACRES:
NA.75
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biological source

maize

Quality Level

200

grade

Hybri-Max™

product line

BioReagent

Assay

≥99.5%

form

powder

technique(s)

cell culture | hybridoma: suitable

impurities

endotoxin, tested

mp

150-152 °C (lit.)

solubility

H2O: 2g + 15 mL (Tested)

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Show Differences

1 of 4

This Item
N9784T3073N3910
Dilution Solution Extract-N-Amp Plant Dilution Solution

D5688

Dilution Solution

血液中和液 sufficient for 100 reactions, sufficient for 1000 reactions

N9784

血液中和液

组织制备溶液 30 mL sufficient for 1,000 extractions

T3073

组织制备溶液

中和液 B

N3910

中和液 B

storage temp.

−20°C

storage temp.

room temp

storage temp.

−20°C

storage temp.

−20°C

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

General description

Glycogen phosphorylase (PYG) exists as brain and muscle isoform. It is expressed in astrocytes and neurons respectively.[1] The PYGM gene is mapped to human chromosome 11q13.1.[2]

Application

D-(+)-Glucose has been used in cell engineering.[3] It has also been used to perform oral glucose tolerance test.[4]

Biochem/physiol Actions

Glycogen phosphorylase, muscle associated (PYGM), is an important contributor to glycogenolysis. Down regulation of PYGM gene is observed in schizophrenia.[1] Mutation in PYGM leads to McArdle disease, a glycogen storage disorder.[5] The PYGM gene is significantly associated with energy production.[6]

Preparation Note

The material may produce a yellowish solution if prepared at a higher concentration than 2g + 15ml.

Legal Information

Hybri-Max is a trademark of Sigma-Aldrich Co. LLC

related product

Product No.
Description
Pricing

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves
  • Specification Sheet

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    Certificates of Analysis (COA)

    Lot/Batch Number
    0000417319
    0000417318
    0000417318
    0000417319
    0000395204

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    Electrical vs manual acupuncture stimulation in a rat model of polycystic ovary syndrome: different effects on muscle and fat tissue insulin signaling
    Johansson J, et al.
    PLoS ONE, 8(1) (2013)
    Comparative metabolic analysis of CHO cell clones obtained through cell engineering, for IgG productivity, growth and cell longevity
    Wilkens CA and Gerdtzen ZP
    PLoS ONE, 10(3) (2015)
    Genetic evaluation of AMPD1, CPT2, and PGYM metabolic enzymes in patients with chronic fatigue syndrome
    Maltese PE, et al.
    Genetics and molecular research : GMR, 15(3), 1-10 (2016)
    Novel variant in the PYGM gene causing late-onset limb-girdle myopathy, ptosis, and camptocormia
    Cheraud C, et al.
    Muscle and Nerve, 57(1), 157-160 (2018)
    CDKN1C/p57 kip2 is a candidate tumor suppressor gene in human breast cancer
    Larson PS, et al.
    BMC Cancer, 8(1), 68-68 (2008)
    View All Related Papers

    Articles

    Aerobic Glycolysis and the Warburg Effect

    Warburg effect enhances glucose to lactate conversion in tumor cells, regardless of oxygen levels; impacting cancer metabolism since 1924.

    Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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