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G3915

Sigma-Aldrich

Gly-Gly

BioPerformance Certified, suitable for cell culture, ≥99%

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Synonym(s):
Diglycine, Glycyl-glycine
Linear Formula:
NH2CH2CONHCH2COOH
CAS Number:
556-50-3
Molecular Weight:
132.12
Beilstein:
1765223
EC Number:
209-127-8
MDL number:
MFCD00008130
UNSPSC Code:
12161700
PubChem Substance ID:
24894917
NACRES:
NA.25

grade

BioPerformance Certified

Quality Level

400

Assay

≥99%

form

powder

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin and total aerobic microbial count, tested

color

white

useful pH range

7.5-8.9

pKa (25 °C)

8.2

mp

255-260 °C

cation traces

heavy metals (as Pb): ≤5 ppm

application(s)

diagnostic assay manufacturing

foreign activity

DNase, RNase, NICKase and protease, none detected

SMILES string

NCC(=O)NCC(O)=O

InChI

1S/C4H8N2O3/c5-1-3(7)6-2-4(8)9/h1-2,5H2,(H,6,7)(H,8,9)

InChI key

YMAWOPBAYDPSLA-UHFFFAOYSA-N

Gene Information

human ... SLC15A1(6564)

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Application


  • Flavor enhancement during the drying of scallop (Patinopecten yessoensis) as revealed by integrated metabolomic and lipidomic analysis.: This study examines the role of Gly-Gly in the flavor enhancement process during the drying of scallops. By using integrated metabolomic and lipidomic analysis, the research identifies key biochemical pathways involved in flavor formation, highlighting the significance of Gly-Gly in the food industry (Wang et al., 2024).

  • A serum metabolomics-based profile in low bone mineral density postmenopausal women.: The research identifies metabolic markers, including Gly-Gly, that are associated with low bone mineral density in postmenopausal women, contributing to the understanding of osteoporosis and potential biomarkers for early diagnosis (Miyamoto et al., 2017).

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Lasse Jenner et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(10), 3812-3816 (2013-02-23)
Here we present an X-ray crystallography structure of the clinically relevant tigecycline antibiotic bound to the 70S ribosome. Our structural and biochemical analysis indicate that the enhanced potency of tigecycline results from a stacking interaction with nucleobase C1054 within the
Francis Impens et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(34), 12432-12437 (2014-08-13)
SUMOylation is an essential ubiquitin-like modification involved in important biological processes in eukaryotic cells. Identification of small ubiquitin-related modifier (SUMO)-conjugated residues in proteins is critical for understanding the role of SUMOylation but remains experimentally challenging. We have set up a
Christopher M Leavitt et al.
Journal of the American Society for Mass Spectrometry, 22(11), 1941-1952 (2011-09-29)
We report vibrational predissociation spectra of the four protonated dipeptides derived from glycine and sarcosine, GlyGlyH(+)•(H(2))(1,2), GlySarH(+)•(D(2))(2), SarGlyH(+)•(H(2))(2), and SarSarH(+)•(D(2))(2), generated in a cryogenic ion trap. Sharp bands were recovered by monitoring photoevaporation of the weakly bound H(2) (D(2)) molecules
P B Armentrout et al.
Journal of the American Society for Mass Spectrometry, 23(4), 632-643 (2011-09-29)
We present a full molecular description of fragmentation reactions of protonated diglycine (H(+)GG) by studying their collision-induced dissociation (CID) with Xe using a guided ion beam tandem mass spectrometer (GIBMS). Analysis of the kinetic energy-dependent CID cross sections provides the
Namrata D Udeshi et al.
Molecular & cellular proteomics : MCP, 12(3), 825-831 (2012-12-26)
Detection of endogenous ubiquitination sites by mass spectrometry has dramatically improved with the commercialization of anti-di-glycine remnant (K-ε-GG) antibodies. Here, we describe a number of improvements to the K-ε-GG enrichment workflow, including optimized antibody and peptide input requirements, antibody cross-linking
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