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G1259

Sigma-Aldrich

α-D-Glucose 1-phosphate disodium salt hydrate

≥95%

Synonym(s):

α-D-Glucopyranose 1-phosphate, Cori ester

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About This Item

Linear Formula:
C6H11O9PNa2 · xH2O
CAS Number:
56401-20-8
Molecular Weight:
304.10 (anhydrous basis)
EC Number:
260-154-1
MDL number:
MFCD00150837
UNSPSC Code:
12352201
PubChem Substance ID:
24895053
NACRES:
NA.25

biological source

synthetic

Assay

≥95%

form

powder

impurities

glucose and starch, essentially free

color

white

solubility

water: 50 mg/mL, clear, colorless

cation traces

Na: 12.5-18.0% (anhydrous)

foreign activity

α-D-glucose 1,6-diphosphate ~1% (usually sufficient to catalyze the assay of phosphoglucomutase)

storage temp.

−20°C

SMILES string

[Na+].[Na+].[H]O[H].OC[C@H]1O[C@H](OP([O-])([O-])=O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C6H13O9P.2Na.H2O/c7-1-2-3(8)4(9)5(10)6(14-2)15-16(11,12)13;;;/h2-10H,1H2,(H2,11,12,13);;;1H2/q;2*+1;/p-2/t2-,3-,4+,5-,6-;;;/m1.../s1

InChI key

YWAUQXHOCBBYLP-FBNUBEQJSA-L

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General description

α-D-Glucose 1-phosphate is converted into D-glucose-6-phosphate by the enzyme phosphoglucomutase.
α-D-Glucose 1-phosphate is the α-anomeric form of glucose which contains a phosphate group on the primary carbon. It can be converted into the deoxysugar CDP-glucose by the enzyme α-D-Glucose-1-phosphate cytidylyltransferase.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

监管及禁止进口产品

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Certificates of Analysis (COA)

Lot/Batch Number
SLBR2458V
SLBG3566V
081M5306V
081M5306
128K3778

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Stanley A Blumenthal
Perspectives in biology and medicine, 55(2), 236-249 (2012-05-31)
In 1945, Earl Sutherland (1915-1974) [corrected] and associates began studies of the mechanism of hormone-induced glycogen breakdown in the liver. In 1956, their efforts culminated in the identification of cyclic AMP, an ancient molecule generated in many cell types in
Joerg Fettke et al.
Plant physiology, 155(4), 1723-1734 (2010-12-01)
Almost all glucosyl transfer reactions rely on glucose-1-phosphate (Glc-1-P) that either immediately acts as glucosyl donor or as substrate for the synthesis of the more widely used Glc dinucleotides, ADPglucose or UDPglucose. In this communication, we have analyzed two Glc-1-P-related
Kyra-Melinda Alexacou et al.
Bioorganic & medicinal chemistry, 18(22), 7911-7922 (2010-10-16)
Glycogen phosphorylase (GP) is a promising target for the treatment of type 2 diabetes. In the process of structure based drug design for GP, a group of 15 aromatic aldehyde 4-(β-d-glucopyranosyl)thiosemicarbazones have been synthesized and evaluated as inhibitors of rabbit
Daniel Decker et al.
Phytochemistry, 79, 39-45 (2012-05-04)
UDP-Glc pyrophosphorylase (UGPase) is an essential enzyme responsible for production of UDP-Glc, which is used in hundreds of glycosylation reactions involving addition of Glc to a variety of compounds. In this study, barley UGPase was characterized with respect to effects
Achim Dickmanns et al.
Journal of molecular biology, 405(2), 461-478 (2010-11-16)
Nucleotide sugars and the enzymes that are responsible for their synthesis are indispensable for the production of complex carbohydrates and, thus, for elaboration of a protective cellular coat for many organisms such as the protozoan parasite Leishmania. These activated sugars
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