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Safety Information

G1259

Sigma-Aldrich

α-D-Glucose 1-phosphate disodium salt hydrate

≥95%

Synonym(s):

α-D-Glucopyranose 1-phosphate, Cori ester

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About This Item

Linear Formula:
C6H11O9PNa2 · xH2O
CAS Number:
Molecular Weight:
304.10 (anhydrous basis)
EC Number:
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:
NACRES:
NA.25

biological source

synthetic

Assay

≥95%

form

powder

impurities

glucose and starch, essentially free

color

white

solubility

water: 50 mg/mL, clear, colorless

cation traces

Na: 12.5-18.0% (anhydrous)

foreign activity

α-D-glucose 1,6-diphosphate ~1% (usually sufficient to catalyze the assay of phosphoglucomutase)

storage temp.

−20°C

SMILES string

[Na+].[Na+].[H]O[H].OC[C@H]1O[C@H](OP([O-])([O-])=O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C6H13O9P.2Na.H2O/c7-1-2-3(8)4(9)5(10)6(14-2)15-16(11,12)13;;;/h2-10H,1H2,(H2,11,12,13);;;1H2/q;2*+1;/p-2/t2-,3-,4+,5-,6-;;;/m1.../s1

InChI key

YWAUQXHOCBBYLP-FBNUBEQJSA-L

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General description

α-D-Glucose 1-phosphate is converted into D-glucose-6-phosphate by the enzyme phosphoglucomutase.
α-D-Glucose 1-phosphate is the α-anomeric form of glucose which contains a phosphate group on the primary carbon. It can be converted into the deoxysugar CDP-glucose by the enzyme α-D-Glucose-1-phosphate cytidylyltransferase.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

监管及禁止进口产品

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Cátia Nunes et al.
Plant physiology and biochemistry : PPB, 63, 89-98 (2012-12-22)
SnRK1 of the SNF1/AMPK group of protein kinases is an important regulatory protein kinase in plants. SnRK1 was recently shown as a target of the sugar signal, trehalose 6-phosphate (T6P). Glucose 6-phosphate (G6P) can also inhibit SnRK1 and given the
Joerg Fettke et al.
Journal of experimental botany, 63(8), 3011-3029 (2012-03-02)
Parenchyma cells from tubers of Solanum tuberosum L. convert several externally supplied sugars to starch but the rates vary largely. Conversion of glucose 1-phosphate to starch is exceptionally efficient. In this communication, tuber slices were incubated with either of four
Yeol Gyun Lee et al.
Journal of microbiology (Seoul, Korea), 48(6), 803-807 (2011-01-12)
To understand the physiological functions of thermostable fructose-1,6-bisphosphatase (TNA1-Fbp) from Thermococcus onnurineus NA1, its recombinant enzyme was overexpressed in Escherichia coli, purified, and the enzymatic properties were characterized. The enzyme showed maximal activity for fructose-1,6-bisphosphate at 95°C and pH 8.0
Xingwei Chen et al.
Journal of biomaterials applications, 27(4), 391-402 (2011-07-14)
The purpose of this study was to evaluate the feasibility of in situ thermosensitive hydrogel based on chitosan in combination with disodium α-d-Glucose 1-phosphate (DGP) for ocular drug delivery system. Aqueous solution of chitosan/DGP underwent sol-gel transition as temperature increased
Sanghamitra Mitra et al.
Glycobiology, 20(10), 1233-1240 (2010-05-29)
Giardia lamblia, which is an important parasitic cause of diarrhea, uses activated forms of glucose to make glycogen and activated forms of mannose to make glycophosphosphoinositol anchors. A necessary step for glucose activation is isomerization of glucose-6-phosphate to glucose-1-phosphate by

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