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G1259

Sigma-Aldrich

α-D-Glucose 1-phosphate disodium salt hydrate

≥95%

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Synonym(s):
α-D-Glucopyranose 1-phosphate, Cori ester
Linear Formula:
C6H11O9PNa2 · xH2O
CAS Number:
56401-20-8
Molecular Weight:
304.10 (anhydrous basis)
EC Number:
260-154-1
MDL number:
MFCD00150837
UNSPSC Code:
12352201
PubChem Substance ID:
24895053
NACRES:
NA.25

biological source

synthetic

Assay

≥95%

form

powder

impurities

glucose and starch, essentially free

color

white

solubility

water: 50 mg/mL, clear, colorless

cation traces

Na: 12.5-18.0% (anhydrous)

foreign activity

α-D-glucose 1,6-diphosphate ~1% (usually sufficient to catalyze the assay of phosphoglucomutase)

storage temp.

−20°C

SMILES string

[Na+].[Na+].[H]O[H].OC[C@H]1O[C@H](OP([O-])([O-])=O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C6H13O9P.2Na.H2O/c7-1-2-3(8)4(9)5(10)6(14-2)15-16(11,12)13;;;/h2-10H,1H2,(H2,11,12,13);;;1H2/q;2*+1;/p-2/t2-,3-,4+,5-,6-;;;/m1.../s1

InChI key

YWAUQXHOCBBYLP-FBNUBEQJSA-L

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General description

α-D-Glucose 1-phosphate is converted into D-glucose-6-phosphate by the enzyme phosphoglucomutase.
α-D-Glucose 1-phosphate is the α-anomeric form of glucose which contains a phosphate group on the primary carbon. It can be converted into the deoxysugar CDP-glucose by the enzyme α-D-Glucose-1-phosphate cytidylyltransferase.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

监管及禁止进口产品

Certificates of Analysis (COA)

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Kyra-Melinda Alexacou et al.
Bioorganic & medicinal chemistry, 18(22), 7911-7922 (2010-10-16)
Glycogen phosphorylase (GP) is a promising target for the treatment of type 2 diabetes. In the process of structure based drug design for GP, a group of 15 aromatic aldehyde 4-(β-d-glucopyranosyl)thiosemicarbazones have been synthesized and evaluated as inhibitors of rabbit
Stanley A Blumenthal
Perspectives in biology and medicine, 55(2), 236-249 (2012-05-31)
In 1945, Earl Sutherland (1915-1974) [corrected] and associates began studies of the mechanism of hormone-induced glycogen breakdown in the liver. In 1956, their efforts culminated in the identification of cyclic AMP, an ancient molecule generated in many cell types in
Joerg Fettke et al.
Plant physiology, 155(4), 1723-1734 (2010-12-01)
Almost all glucosyl transfer reactions rely on glucose-1-phosphate (Glc-1-P) that either immediately acts as glucosyl donor or as substrate for the synthesis of the more widely used Glc dinucleotides, ADPglucose or UDPglucose. In this communication, we have analyzed two Glc-1-P-related
Cátia Nunes et al.
Plant physiology and biochemistry : PPB, 63, 89-98 (2012-12-22)
SnRK1 of the SNF1/AMPK group of protein kinases is an important regulatory protein kinase in plants. SnRK1 was recently shown as a target of the sugar signal, trehalose 6-phosphate (T6P). Glucose 6-phosphate (G6P) can also inhibit SnRK1 and given the
Xingwei Chen et al.
Journal of biomaterials applications, 27(4), 391-402 (2011-07-14)
The purpose of this study was to evaluate the feasibility of in situ thermosensitive hydrogel based on chitosan in combination with disodium α-d-Glucose 1-phosphate (DGP) for ocular drug delivery system. Aqueous solution of chitosan/DGP underwent sol-gel transition as temperature increased
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