G1149
L-Glutamic acid potassium salt monohydrate
BioReagent, suitable for insect cell culture, ≥99% (HPLC)
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All Photos(3)
Synonym(s):
(S)-2-Aminopentanedioic acid, L-α-Aminoglutaric acid potassium salt, L-2-Aminopentanedioic acid potassium salt, Glu, Potassium L-glutamate
Empirical Formula (Hill Notation):
C5H8KNO4 · H2O
CAS Number:
Molecular Weight:
203.23
Beilstein:
3637377
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.75
Recommended Products
product line
BioReagent
Quality Level
Assay
≥99% (HPLC)
form
powder
technique(s)
cell culture | insect: suitable
color
white
SMILES string
O.[K+].N[C@@H](CCC([O-])=O)C(O)=O
InChI
1S/C5H9NO4.K.H2O/c6-3(5(9)10)1-2-4(7)8;;/h3H,1-2,6H2,(H,7,8)(H,9,10);;1H2/q;+1;/p-1/t3-;;/m0../s1
InChI key
XIBUKSQTWSKJMQ-QTNFYWBSSA-M
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General description
L-Glutamic acid, an amino acid is mainly found in various food products in its free form. It is ubiquitously present in the brain of mammals.
Application
L-Glutamic acid potassium salt monohydrate has been used as a component in KG buffer for cardiomyocyte isolation and culture.
Biochem/physiol Actions
L-Glutamic acid plays a major role in several metabolic pathways. It acts as excitatory neurotransmitter in the cerebral cortex. An plays a key role in learning, memory and brain aging processes. It is involved in neuronal differentiation, migration and survival in the developing brain. High levels of glutamic acid is observed in Alzheimer′s, Parkinson′s diseases and epilepsy.
Agonist at kainate, NMDA, and quisqualate receptors; an excitatory amino acid neurotransmitter.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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The HCM-linked W792R mutation in cardiac myosin-binding protein C reduces C6 FnIII domain stability
Smelter DF, et al.
American Journal of Physiology. Heart and Circulatory Physiology, 314(6), H1179-H1191 (2018)
Robbin Schnieders et al.
Current protocols in nucleic acid chemistry, 82(1), e116-e116 (2020-09-23)
NMR spectroscopy is a potent method for the structural and biophysical characterization of RNAs. The application of NMR spectroscopy is restricted in RNA size and most often requires isotope-labeled or even selectively labeled RNAs. Additionally, new NMR pulse sequences, such
Stability and solution structure of binary and ternary Cu (II) complexes with l-glutamic acid and diamines as well as adducts in metal-free systems in aqueous solution
Bregier-JR
Journal of Solution Chemistry, 43(12), 2144-2162 (2014)
Cell Type-Specific Imaging of Calcium Signaling in Arabidopsis thaliana Seedling Roots Using GCaMP3.
William Krogman et al.
International journal of molecular sciences, 21(17) (2020-09-06)
Cytoplasmic calcium ([Ca2+]cyt) is a well-characterized second messenger in eukaryotic cells. An elevation in [Ca2+]cyt levels is one of the earliest responses in plant cells after exposure to a range of environmental stimuli. Advances in understanding the role of [Ca2+]cyt
Oksana Forostyak et al.
Stem cells and development, 22(10), 1506-1521 (2013-01-09)
Human embryonic stem cell-derived neural precursors (hESC NPs) are considered to be a promising tool for cell-based therapy in central nervous system injuries and neurodegenerative diseases. The Ca(2+) ion is an important intracellular messenger essential for the regulation of various
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