Skip to Content
Merck
CN
All Photos(2)

Documents

FLAAS

Sigma-Aldrich

Adenosine 5′-triphosphate (ATP) disodium salt hydrate

vial of ~1 mg ATP

Sign Into View Organizational & Contract Pricing
All Photos(2)
Synonym(s):
ATP disodium hydrate
Linear Formula:
C10H14N5O13P3Na2 · xH2O
CAS Number:
34369-07-8
Molecular Weight:
551.14 (anhydrous basis)
EC Number:
213-579-1
MDL number:
MFCD00150755
UNSPSC Code:
12352202
eCl@ss:
32160414
PubChem Substance ID:
24895005
NACRES:
NA.26

biological source

bacterial (Corynebacterium sp)

Quality Level

200

Assay

≥90%

form

lyophilized powder

packaging

vial of ~1 mg ATP

storage temp.

−20°C

SMILES string

Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O

InChI

1S/C10H16N5O13P3.2Na.H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;;1H2/q;2*+1;/p-2/t4-,6-,7-,10-;;;/m1.../s1

InChI key

NTBQNWBHIXNPRU-MSQVLRTGSA-L

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

Adenosine 5′-triphosphate (ATP) disodium salt hydrate has been:
  • used as a standard to measure ATP by bioluminescence method
  • used in kinase buffer to assess the interaction between death-associated protein kinases (DAPK2) and 14-3-3-β
  • used as a standard in ATP colorimetric assay

Biochem/physiol Actions

Adenosine 5′-triphosphate (ATP) is one of the nucleoside triphosphate present in living system. It controls various biologic processes such as glucose metabolism, muscle contraction and neurotransmission. Apart from this, ATP serves as an important energy source for the cell. Administration of ATP might be useful in the treatment of non-small-cell lung cancer.
Adenosine 5′-triphosphate was shown to have inhibitory effects on the inflammatory response by abrogating secretion of TNF-α and promoting secretion of Interleukin-10.
P2 purinergic agonist; increases activity of Ca2+-activated K+ channels; substrate for ATP-dependent enzyme systems

Quantity

Each vial contains ~1.2 mg of Na2ATP • 3H2O equivalent to ~1.0 mg of ATP (2.0 μmol). Actual amount printed on the label.

Preparation Note

Prepared to be substantially vanadium-free.

WGK

WGK 2

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Els L R Swennen et al.
European journal of immunology, 35(3), 852-858 (2005-02-19)
In vitro studies suggest that extracellular nucleotides and nucleosides may be important regulators of inflammatory and immune responses. Most studies with adenosine 5'-triphosphate (ATP) have been performed in cell lines, which are remote from the human situation. The purpose of
Jie Ge et al.
Journal of medicinal chemistry, 49(15), 4606-4615 (2006-07-21)
17-Allylamino-17-demethoxygeldanamycin (17-AAG)1 is a semisynthetic inhibitor of the 90 kDa heat shock protein (Hsp90) currently in clinical trials for the treatment of cancer. However, 17-AAG faces challenging formulation issues due to its poor solubility. Here we report the synthesis and
Identification of novel death-associated protein kinase 2 interaction partners by proteomic screening coupled with bimolecular fluorescence complementation
Geering B, et al.
Molecular and Cellular Biology, 36(1), 132-143 (2016)
Necrostatin-1 attenuates mitochondrial dysfunction in neurons and astrocytes following neonatal hypoxia--ischemia
Chavez-Valdez R, et al.
Neuroscience, 219, 192-203 (2012)
Francisco J Adrián et al.
Nature chemical biology, 2(2), 95-102 (2006-01-18)
Chronic myelogenous leukemia (CML) is a myeloproliferative disorder characterized at the molecular level by the expression of Bcr-abl, a 210-kDa fusion protein with deregulated tyrosine kinase activity. Encouraged by the clinical validation of Bcr-abl as the target for the treatment
View All Related Papers

Protocols

HPLC Analysis of Adenosine on Supelcosil™ LC-18-T

HPLC separation of nucleotide salts ensures high purity for biochemical studies and research applications.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service