F7879
Ferritin, cationized from horse spleen
10 mg/mL in 0.15 M NaCl
Product Name
Ferritin, cationized from horse spleen, 10 mg/mL in 0.15 M NaCl
biological source
horse spleen
sterility
sterile-filtered
form
liquid
concentration
10 mg/mL in 0.15 M NaCl
technique(s)
cell culture | mammalian: suitable
electron microscopy: suitable
UniProt accession no.
storage temp.
2-8°C
Quality Level
Gene Information
horse ... FTL(100051593)
Application
A cationic derivative used to label negatively charged cell membranes for visualization by electron microscopy.
Ferritin is an iron storage protein that plays a central role in iron metabolism, and may be elevated in inflammatory or malignant diseases. It has been used in studies as an indicator of body iron supply, but may prove inaccurate in in the presence of chronic inflammation.
Ferritin, cationized from horse spleen has been used:
- to incubate amoebae (106) in the study, to determine whether trophozoites are able to take up ferritin and internalise this protein for their growth in axenic culture
- to determine phagosome-lysosome fusion by electron microscopy
- to label freshly excised chick optic tecta in serum free incubation medium
Biochem/physiol Actions
Ferritin holds iron at its ferric state (Fe3+). The core of ferritin has the capability to hold 4500 iron molecules. It is essential to store iron in vertebrates. Ferritin is also essential to store and transport iron in invertebrates. It plays a key role in dietary iron absorption.
General description
Ferritin, an iron-storage protein is usually present in the liver and spleen in mammals. Iron and ferritin are distributed relatively same in the eye. Ferritin is made up of heavy and light chains.
Preparation Note
Prepared by coupling horse spleen ferritin with N,N-dimethyl-1,3-propanediamine (DMPA).
Storage Class
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
低风险生物材料
This item has
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Fabrizio Bardelli et al.
Scientific reports, 7, 44862-44862 (2017-03-24)
Once penetrated into the lungs of exposed people, asbestos induces an in vivo biomineralisation process that leads to the formation of a ferruginous coating embedding the fibres. The ensemble of the fibre and the coating is referred to as asbestos
Interaction of Legionella pneumophila with Acanthamoeba castellanii: uptake by coiling phagocytosis and inhibition of phagosome-lysosome fusion.
Bozue J A and Johnson W
Infection and Immunity, 64(2), 668-673 (1996)
Recycling of plasmalemma in chick tectal growth cones
Cheng, TP and Reese, TS
The Journal of Neuroscience, 7(6), 1752-1759 (1987)
Jennifer R Charlton et al.
BMC nephrology, 24(1), 178-178 (2023-06-19)
A significant barrier to biomarker development in the field of acute kidney injury (AKI) is the use of kidney function to identify candidates. Progress in imaging technology makes it possible to detect early structural changes prior to a decline in
Iron-Induced Retinal Damage
Handbook of nutrition, diet, and the eye, 619-626 (2014)
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service