F5537
Anti-Fibroblast Growth Factor-Basic antibody produced in rabbit
IgG fraction of antiserum, buffered aqueous solution
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Synonym(s):
Anti-FGF2
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biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
IgG fraction of antiserum
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
human
technique(s)
dot blot: 1:10,000
neutralization: suitable
radioimmunoassay: 1:10,000
western blot: suitable
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
Gene Information
human ... FGF2(2247)
Specificity
The antibody does not cross-react with recombinant human FGF1, IL-1α, IL-1β, IL-3, or TNF-α, nor with mouse or human IL-6.
Immunogen
recombinant human FGF2 expressed in Escherichia coli.
Physical form
Solution in phosphate buffered saline, 0.2 μm filtered.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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WGK
nwg
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Certificates of Analysis (COA)
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B Spencer et al.
Molecular therapy : the journal of the American Society of Gene Therapy, 3(5 Pt 1), 746-756 (2001-05-18)
Fibroblast growth factor 2 (bFGF, FGF2) exhibits mitogenic, angiogenic, wound healing, and neuroprotective properties. Infusion of FGF2 in vivo to treat neurodegenerative disorders in animal models results in increased survival of damaged neurons, but these effects are transient. To test
A Aigner et al.
International journal of cancer, 92(4), 510-517 (2001-04-17)
Fibroblast growth factors FGF-1 (aFGF) and FGF-2 (bFGF) are found in most embryonic and adult normal and tumor tissues, where they are immobilized in the extracellular matrix (ECM). Mobilization of these FGFs is part of a tightly controlled process resulting
Angiogenic cytokines. Quantitative and functional analysis.
Angelika Eggert et al.
Methods in molecular biology (Clifton, N.J.), 215, 117-133 (2003-01-07)
Min Qin et al.
American journal of respiratory cell and molecular biology, 32(3), 211-217 (2005-01-01)
We compared native Adenoviral (Ad) vectors to a basic Fibroblast Growth Factor-retargeted Adenovirus (FGF2-Ad) for gene delivery into a diverse panel of lung cancer cells in vitro and xenografts in vivo. Cells were first evaluated for vector-specific receptor expression. Marked
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