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F3667

Sigma-Aldrich

Fibronectin Adhesion-promoting Peptide

≥95% (HPLC)

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Empirical Formula (Hill Notation):
C47H74N16O10
CAS Number:
125720-21-0
Molecular Weight:
1023.19
MDL number:
MFCD00237001
UNSPSC Code:
12352209
PubChem Substance ID:
329799700
NACRES:
NA.32

biological source

synthetic (organic)

Quality Level

200

Assay

≥95% (HPLC)

form

powder

composition

Peptide content, ~70%

storage temp.

−20°C

SMILES string

CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]2CCCN2C(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)Cc3c[nH]c4ccccc34)C(O)=O

InChI

1S/C47H74N16O10/c1-4-25(2)37(45(72)73)61-41(68)32(14-8-20-55-47(52)53)58-38(65)26(3)57-40(67)31(13-7-19-54-46(50)51)59-42(69)34-15-9-21-62(34)44(71)35-16-10-22-63(35)43(70)33(17-18-36(49)64)60-39(66)29(48)23-27-24-56-30-12-6-5-11-28(27)30/h5-6,11-12,24-26,29,31-35,37,56H,4,7-10,13-23,48H2,1-3H3,(H2,49,64)(H,57,67)(H,58,65)(H,59,69)(H,60,66)(H,61,68)(H,72,73)(H4,50,51,54)(H4,52,53,55)/t25-,26-,29-,31-,32-,33-,34-,35-,37-/m0/s1

InChI key

OVXIMRGEBNSORH-PJRZOMOUSA-N

Amino Acid Sequence

Trp-Gln-Pro-Pro-Arg-Ala-Arg-Ile

Other Notes

Sequence found in the carboxy-terminal heparin-binding domain of fibronectin.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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A Woods et al.
Molecular biology of the cell, 4(6), 605-613 (1993-06-01)
Cell adhesion to extracellular matrix molecules such as fibronectin involves complex transmembrane signaling processes. Attachment and spreading of primary fibroblasts can be promoted by interactions of cell surface integrins with RGD-containing fragments of fibronectin, but the further process of focal

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