F3272
Inulin–FITC
from dahlia tuber
Synonym(s):
Fluorescein isothiocyanate–inulin
Product Name
Inulin–FITC, from dahlia tuber
form
powder
biological source
dahlia tuber
mol wt
2,000-5,000
color
light yellow to dark yellow, to dark orange
solubility
water: soluble, clear
storage temp.
2-8°C
Quality Level
Application
- Development and validation of bioengineered intestinal tubules for translational research aimed at safety and efficacy testing of drugs and nutrients.: This study employs Inulin–FITC to investigate the absorption characteristics of bioengineered intestinal models, providing critical data on gut permeability and nutrient interaction, which is crucial for pharmaceutical and nutritional research (Jochems et al., 2019).
- Role of Vitamin D in Maintaining Renal Epithelial Barrier Function in Uremic Conditions.: Utilizes Inulin–FITC to measure the efficacy of Vitamin D in preserving renal barrier function under stress conditions, which could lead to new treatments for chronic kidney disease (Mihajlovic et al., 2017).
- Inhibition of p38 mitogen-activated protein kinase attenuates butyrate-induced intestinal barrier impairment in a Caco-2 cell monolayer model.: This investigation highlights the role of Inulin–FITC in studying the protective effects of kinase inhibition on intestinal barriers, relevant for gastrointestinal disorder treatments (Huang et al., 2014).
- Measurement of glomerular filtration rate in conscious mice using FITC-inulin clearance.: Demonstrates the utility of Inulin–FITC in precise, non-invasive measurements of renal function, essential for nephrology research and therapy development (Qi and Breyer, 2009).
- PPAR gamma agonist normalizes glomerular filtration rate, tissue levels of homocysteine, and attenuates endothelial-myocyte uncoupling in alloxan induced diabetic mice.: Incorporates Inulin–FITC to assess the efficacy of a PPAR gamma agonist in diabetic nephropathy, providing insights into metabolic disease management (Rodriguez et al., 2008).
Other Notes
To gain a comprehensive understanding of our extensive range of Oligosaccharides for your research, we encourage you to visit our Carbohydrates Category page.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Richard B van Breemen et al.
Expert opinion on drug metabolism & toxicology, 1(2), 175-185 (2006-08-23)
Caco-2 cells are a human colon epithelial cancer cell line used as a model of human intestinal absorption of drugs and other compounds. When cultured as a monolayer, Caco-2 cells differentiate to form tight junctions between cells to serve as
Walter E Rodriguez et al.
International journal of biological sciences, 4(4), 236-244 (2008-08-12)
Homocysteine (Hcy) is an independent cardiovascular risk factor; however, in diabetes, the role of tissue Hcy leading to cardiac dysfunction is unclear. To determine whether tissue Hcy caused endothelial-myocyte uncoupling and ventricular dysfunction in diabetes. Diabetes was created in C57BL/6J
Grant Backer et al.
Physiological genomics, 50(8), 543-552 (2018-04-14)
Mesangial matrix expansion is an important process in the initiation of chronic kidney disease, yet the genetic factors driving its development are unknown. Our previous studies have implicated Far2 as a candidate gene associated with differences in mesangial matrix expansion
M A Storr et al.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 22(7), 787-796 (2010-02-26)
Cannabinoid type 1 (CB(1)) receptors are involved in the regulation of gastrointestinal (GI) motility and secretion. Our aim was to characterize the roles of the CB(1) receptor on GI motility and secretion in vitro and in vivo by using different
Jun Sugama et al.
Diabetes, obesity & metabolism, 23(1), 86-96 (2020-09-08)
To examine the effects of an enteropeptidase inhibitor, SCO-792, on kidney function in rats. The pharmacological effects of SCO-792 were evaluated in Wistar fatty (WF) rats, a rat model of diabetic kidney disease (DKD). Oral administration of SCO-792 increased faecal
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