F2756
Fluorescein di(β-D-galactopyranoside)
Synonym(s):
FDG
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About This Item
Empirical Formula (Hill Notation):
C32H32O15
CAS Number:
Molecular Weight:
656.59
NACRES:
NC.07
PubChem Substance ID:
UNSPSC Code:
12352201
MDL number:
assay
≥98% (HPLC)
Quality Level
form
powder
solubility
methanol: 20 mg/mL, clear, yellow
storage temp.
−20°C
SMILES string
OC[C@H]1O[C@@H](Oc2ccc3c(Oc4cc(O[C@@H]5O[C@H](CO)[C@H](O)[C@H](O)[C@H]5O)ccc4C36OC(=O)c7ccccc67)c2)[C@H](O)[C@@H](O)[C@H]1O
InChI
1S/C32H32O15/c33-11-21-23(35)25(37)27(39)30(45-21)42-13-5-7-17-19(9-13)44-20-10-14(43-31-28(40)26(38)24(36)22(12-34)46-31)6-8-18(20)32(17)16-4-2-1-3-15(16)29(41)47-32/h1-10,21-28,30-31,33-40H,11-12H2/t21-,22-,23+,24+,25+,26+,27-,28-,30-,31-/m1/s1
InChI key
ZTOBILYWTYHOJB-WBCGDKOGSA-N
General description
Fluorogenic substrate for β-galactosidase
Application
Fluorescein di(β-D-galactopyranoside) has been used as a substrate in β-galactosidase assay.
Fluorescein di(β-D-galactopyranoside) (FDG) has been used for the detection of gene expression via FACS (fluorescence-activated cell sorting).
Biochem/physiol Actions
Fluorescein di (β-D-galactopyranoside) (FDG) results in fluorescence after being hydrolyzed to fluorescein by β-galactosidase. It gives fluorescence proportional to the enzymatic activity. This molecule is mainly required for the detection of gene expression in transfected cells when using β-galactosidase (Lac Z) as a reporter gene.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
涉药品监管产品
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Michael Peter Jones et al.
Radiation oncology (London, England), 14(1), 140-140 (2019-08-08)
To investigate the prognostic significance of positron emission tomography (PET) parameters from F-18 fluorodeoxyglucose (FDG) PET scans performed pre- and post- chemo-radiotherapy (CRT) for squamous cell carcinoma of the anal canal (AC). From January 2013 to January 2017, 19 patients
Jose M Anton-Rodriguez et al.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 40(6), 826-835 (2019-04-30)
To investigate whether [F]fluorothymidine (FLT) and/or [F]fluorodeoxyglucose (FDG) positron emission tomography (PET) can differentiate growth in neurofibromatosis 2 (NF2) related vestibular schwannomas (VS) and to evaluate the importance of PET scanner spatial resolution on measured tumor uptake. Six NF2 patients
A fluorimetric method using fluorescein di-?-D-galactopyranoside for quantifying the senescence-associated ?-galactosidase activity in human foreskin fibroblast Hs68 cells.
Yang NC and Hu ML
Analytical Biochemistry, 325, 337-343 (2004)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| F2756-1MG | 04061833613009 |
| F2756-25MG | 04061833613269 |
| F2756-5MG | 04061833613290 |