F134
S(+)-α-Fluoromethylhistidine hydrochloride
solid
Synonym(s):
MK-453, S(+)-α-FMH
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
Empirical Formula (Hill Notation):
C7H10FN3O2 · HCl
Molecular Weight:
223.63
MDL number:
UNSPSC Code:
12352200
Recommended Products
form
solid
color
off-white
solubility
H2O: 18 mg/mL
DMSO: 6.3 mg/mL
SMILES string
Cl.N[C@@](CF)(Cc1c[nH]cn1)C(O)=O
Biochem/physiol Actions
Histidine decarboxylase inhibitor.
Regulatory Information
新产品
Choose from one of the most recent versions:
Certificates of Analysis (COA)
Lot/Batch Number
Don't see the Right Version?
If you require a particular version, you can look up a specific certificate by the Lot or Batch number.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
K Sugimoto et al.
Journal of neurochemistry, 65(2), 791-797 (1995-08-01)
The mast cell-deficient [Ws/Ws (White spotting in the skin)] rat was investigated with regard to the origin of histamine in the brain. No mast cells were detected in the pia mater and the perivascular region of the thalamus of Ws/Ws
G D Prell et al.
Journal of neurochemistry, 66(5), 2153-2159 (1996-05-01)
In mammalian brain, histamine is known to be metabolized solely by histamine methyltransferase (HMT), forming tele-methylhistamine (t-MH), then tele-methylimidazoleacetic acid (t-MIAA). We previously showed that imidazoleacetic acid (IAA), a GABA agonist, and histamine's metabolite in the periphery, is present in
Long-term depletion of brain histamine induced by α-fluoromethylhistidine increases feeding-associated locomotor activity in mice with a modulation of brain amino acid levels.
Sakai, et al.
Behavioural Brain Research, 14, 83-88 (1995)
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service