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EMU086381

Sigma-Aldrich

MISSION® esiRNA

targeting mouse Glp1r

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

description

Powered by Eupheria Biotech

Quality Level

100

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

CTGGTGGAAGGCGTGTATCTATACACACTGCTGGCCTTCTCGGTGTTCTCGGAGCAGCGCATCTTCAAGCTGTATCTGAGCATAGGCTGGGGAGTTCCGCTGCTGTTCGTTATCCCATGGGGGATTGTCAAGTATCTCTATGAGGACGAGGGCTGCTGGACTAGGAACTCCAATATGAACTACTGGCTCATCATCCGATTGCCCATTCTCTTTGCTATCGGCGTCAACTTTCTTATCTTCATCCGTGTCATCTGCATAGTGGTCTCCAAACTGAAGGCTAATCTCATGTGCAAGACTGACATCAAATGCAGGCTTGCCAAGTCCACTCTGACTCTCATCCCCCTTCTGGGGACACATGAAGTCATCTTTGCCTTTGTGATGGACGAACACGCCCGAGGAACCCTACGCTTCATCAAGCTGTTCACAGAACTCTCCTTCACTTCCTTCCAGGGCTTGATGGTGGCTATCCTGTACTGCTTTGTCAACAATGAGGTCCAGATGGAGTTTCGGAAATGCTG

Ensembl | mouse accession no.

ENSMUSG00000024027

NCBI accession no.

NM_021332

shipped in

ambient

storage temp.

−20°C

Gene Information

mouse ... GLP1R(14652) , Glp1r(14652)

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General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Jun-Kun Zhan et al.
International journal of cardiology, 189, 188-193 (2015-04-22)
Arterial calcification is a common event in cardiovascular pathogenesis. Osteoblastic differentiation of vascular smooth muscle cells (VSMCs) is the most important cytopathologic foundation of arterial calcification. Glucagon-like peptide-1 (GLP-1) exerts multiple cardioprotective actions beyond insulinotropic effects through GLP-1 receptor (GLP-1R).

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