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EMU011901

Sigma-Aldrich

MISSION® esiRNA

targeting mouse Ror2

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

description

Powered by Eupheria Biotech

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

GCTGGTGTACGACAAGCTGAACGTGAGGATCTCAGACTTGGGCCTCTTCCGTGAGGTATACTCCGCAGATTACTACAAACTCATGGGCAATTCACTGCTGCCCATCCGCTGGATGTCCCCCGAGGCCGTCATGTATGGAAAGTTCTCCATCGACTCTGACATCTGGTCCTACGGTGTGGTCCTCTGGGAGGTCTTTAGCTACGGCCTGCAGCCCTACTGTGGGTACTCCAACCAGGACGTGGTGGAGATGATCCGGAGCCGGCAGGTGCTGCCCTGTCCGGATGACTGCCCCGCCTGGGTCTATGCCCTCATGATTGAATGCTGGAATGAGTTCCCAAGCCGGAGGCCCCGCTTTAAGGACATCCACAGCCGGCTCCGGTCCTGGGGCAACCTATCCAACTATAATAGTTCCGCGCAGACCT

Ensembl | mouse accession no.

ENSMUSG00000021464

NCBI accession no.

NM_013846

shipped in

ambient

storage temp.

−20°C

Gene Information

mouse ... ROR2(26564) , Ror2(26564)

Related Categories

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Claire Henry et al.
Oncotarget, 6(37), 40310-40326 (2015-10-31)
In recent years, the Wnt signalling pathway has been implicated in epithelial ovarian cancer and its members have potential as diagnostic, prognostic and therapeutic targets. Here we investigated the role of two Wnt receptor tyrosine kinases (RTKs), ROR1 and ROR2
Marie R Webster et al.
Pigment cell & melanoma research, 28(2), 184-195 (2014-11-20)
We have previously shown that Wnt5A drives invasion in melanoma. We have also shown that Wnt5A promotes resistance to therapy designed to target the BRAF(V600E) mutation in melanoma. Here, we show that melanomas characterized by high levels of Wnt5A respond

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