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EHU099701

Sigma-Aldrich

MISSION® esiRNA

targeting human AKAP9 (1)

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UNSPSC Code:
41105324
NACRES:
NA.51

description

Powered by Eupheria Biotech

Quality Level

100

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

GAGTTAGGAGAACATGGAAAGGAAATTTTATTATCAAATAGTGATCCCCATGATATACCAGAATCAAAGGACTGTGTGCTGACTATTTCAGAAGAAATGTTCTCCAAAGATAAAACATTTATAGTTAGACAGTCTATTCATGATGAGATTTCAGTGTCAAGCATGGATGCTTCTAGACAACTAATGTTGAATGAAGAACAGTTGGAAGATATGAGACAGGAACTTGTACGACAATACCAAGAACATCAACAGGCAACGGAATTGTTAAGGCAAGCACATATGCGGCAAATGGAGAGACAGCGAGAAGACCAGGA

Ensembl | human accession no.

ENSG00000127914

NCBI accession no.

NM_005751

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... AKAP9(10142) , AKAP9(10142)

General description

MISSION esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Epithelial-to-mesenchymal transition (EMT) plays a role in chronic obstructive pulmonary diseases (COPD). Cyclic adenosine monophosphate (cAMP) can inhibit transforming growth factor-β1 (TGF-β1) mediated EMT. Although compartmentalization via A-kinase anchoring proteins (AKAPs) is central to cAMP signaling, functional studies regarding their
Shoji Hata et al.
Nature cell biology, 21(9), 1138-1151 (2019-09-05)
One of the first steps in mitotic spindle assembly is the dissolution of the centrosome linker followed by centrosome separation driven by EG5, a tetrameric plus-end-directed member of the kinesin-5 family. However, even in the absence of the centrosome linker

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