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Key Documents

Safety Information

EHU088911

Sigma-Aldrich

MISSION® esiRNA

targeting human GCNT2

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1 MG
CN¥1,737.73

CN¥1,737.73


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1 MG
CN¥1,737.73

About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

CN¥1,737.73


Please contact Customer Service for Availability

description

Powered by Eupheria Biotech

Quality Level

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

CAGGCCCAGGAGATCAGTAATTACAAATTAAGGGTTAAATCAGAGATTATTCAACAGAGAGGGAGAAAGGAGGAGACAGAGGGAGGACCTGTTGTGTTCCAGCCATTCTGGTATTCCTTTATGTATCTAATTTCATTCAAACCTCACAACAGTCTTGTGAGGCCCTTATATAATTACTCCCATTTTGCAGATGAAGTAACTGAGGCTTAGAAAGGTTAATAGCACCGGGGAACAATTTCTCTGGGTGAGAATTGGGACTCTGTTGCTGGTCTTCTCAGTTCATTTCCTGAGGTGGATTTACTGAGAGAAGGTGAAATAAAGCCATATTTAGTATACCAGAGAAGGTAGATTTTAAGAATGGTCTCAGTGTTAATACTGAGAAAAAGTCCTGTCAGTTCAG

Ensembl | human accession no.

NCBI accession no.

shipped in

ambient

storage temp.

−20°C

Gene Information

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This Item
A4414G2500C3400
assay

≥70% protein basis (biuret)

assay

≥99% (agarose gel electrophoresis)

assay

70-90% (biuret)

assay

87-94% protein basis

biological source

Porcine muscle

biological source

Porcine

biological source

Porcine skin

biological source

bovine milk

technique(s)

electrophoresis: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

activity assay: suitable, electrophoresis: suitable, immunocytochemistry: suitable

form

lyophilized powder (contains Tris buffer salts)

form

lyophilized powder

form

powder

form

powder

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

-

storage temp.

-

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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    N Giovannone et al.
    Nature communications, 9(1), 3287-3287 (2018-08-19)
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    Triple-negative breast cancers (TNBCs) are highly aggressive cancers that lack targeted therapies. However, EGFR is frequently activated in a subset of TNBCs and represents a viable clinical target. Because the endocytic adaptor protein Endophilin A2 (SH3GL1/Endo II) has been implicated
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    PloS one, 10(7), e0132655-e0132655 (2015-07-24)
    Melanomas cause over 76% of skin cancer deaths annually. Phosphatidylinositol 3-kinase (PI3K)-AKT-mammalian target of rapamycin (mTOR) signaling pathway is important for melanoma initiation and progression. In the current study, we evaluated the potential anti-melanoma effect of VS-5584, a novel and
    Alexandre K Rouquette-Jazdanian et al.
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    Linker for Activation of T cells (LAT) is an adapter protein that is essential for T cell function. Knock-in mice with a LAT mutation impairing calcium flux develop a fatal CD4+ lymphoproliferative disease. miR-155 is a microRNA that is correlated

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