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EHU085451

Sigma-Aldrich

MISSION® esiRNA

targeting human DSC3

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100 μL
CN¥4,686.02

CN¥4,686.02

Estimated to ship onMarch 25, 2025Details

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100 μL
CN¥4,686.02

About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

CN¥4,686.02

Estimated to ship onMarch 25, 2025Details

description

Powered by Eupheria Biotech

Quality Level

100

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

CACAGGCGTAATCACCACAGTCTCTCATTATTTGGACAGAGAGGTTGTAGACAAGTACTCATTGATAATGAAAGTACAAGACATGGATGGCCAGTTTTTTGGATTGATAGGCACATCAACTTGTATCATAACAGTAACAGATTCAAATGATAATGCACCCACTTTCAGACAAAATGCTTATGAAGCATTTGTAGAGGAAAATGCATTCAATGTGGAAATCTTACGAATACCTATAGAAGATAAGGATTTAATTAACACTGCCAATTGGAGAGTCAATTTTACCATTTTAAAGGGAAATGAAAATGGACATTTCAAAATCAGCACAGACAAAGAAACTAATGAAGGTGTTCTTTCTGTTGTAAAGCCACTGAATTATGAAGAAAACCGTCAAGTGAACCTGG

Ensembl | human accession no.

ENSG00000134762

NCBI accession no.

NM_001941

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... DSC3(1825) , DSC3(1825)

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MISSION® esiRNA targeting human DSC3

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esiRNA cDNA target sequence

CACAGGCGTAATCACCACAGTCTCTCATTATTTGGACAGAGAGGTTGTAGACAAGTACTCATTGATAATGAAAGTACAAGACATGGATGGCCAGTTTTTTGGATTGATAGGCACATCAACTTGTATCATAACAGTAACAGATTCAAATGATAATGCACCCACTTTCAGACAAAATGCTTATGAAGCATTTGTAGAGGAAAATGCATTCAATGTGGAAATCTTACGAATACCTATAGAAGATAAGGATTTAATTAACACTGCCAATTGGAGAGTCAATTTTACCATTTTAAAGGGAAATGAAAATGGACATTTCAAAATCAGCACAGACAAAGAAACTAATGAAGGTGTTCTTTCTGTTGTAAAGCCACTGAATTATGAAGAAAACCGTCAAGTGAACCTGG

esiRNA cDNA target sequence

AGACAGGCATGGTTTAGTTGCAACACATATGTTAACAGTGAGAGTATGTGACTGTTCAACTCCATCTGAGTGTAGAATGAAGGATAAAAGTACAAGAGACGTTAGACCAAATGTAATACTTGGAAGATGGGCTATTCTTGCTATGGTGTTGGGTTCTGTATTGTTATTATGTATTCTGTTTACATGTTTCTGTGTCACTGCTAAGAGAACAGTCAAGAAATGTTTTCCAGAAGACATAGCCCAGCAAAATTTAATTGTATCAAATACTGAAGGACCTGGAGAAGAAGTAACGGAAGCAAATATTAGACTCCCCATGCAGACATCCAACATTTGTGACACAAGCATGTCTGTTGGTACTGTTGGTGGCCAGGGAATCAAAACACAGCAAAGTTTTGAGATGGTCAAAGGAGGCTACACTTTGGATTCCAACAAAGGAGGTGGAC

esiRNA cDNA target sequence

TCCTTGACCTGTTCATGCTGTACGTGCTGGTGACGGAGAAGGGCGGCCTCGTGGAGGTCATCAACAAGAAGCTGTGGCGTGAGATCACCAAGGGCCTCAACCTGCCCACGTCCATCACCAGTGCAGCCTTCACCCTGCGGACCCAATACATGAAGTACCTGTACCCCTACGAGTGTGAGAAGCGGGGCCTCAGTAACCCCAATGAGCTCCAGGCAGCCATAGACAGCAACCGACGGGAGGGCCGGCGCCAGAGCTTTGGTGGCTCCCTCTTTGCCTACTCGCCAGGCGGGGCACACGGCATGCTCTCCTCACCCAAGCTACCCGTGTCCTCCCTGGGCCTGGCCGCAAGCACCAATGGCAGCTCCATCACCCCCGCCCCTAAGATCAAGAAAGAGGAGGACTCAGCCA

esiRNA cDNA target sequence

CAAACCCACCATGTCATCTGCGGAGATTGTTGCGGTTGATCCTGATGAGCCTATCCATGGCCCACCCTTTGACTTTAGTCTGGAGAGTTCTACTTCAGAAGTACAGAGAATGTGGAGACTGAAAGCAATTAATGATACAGCAGCACGTCTTTCCTATCAGAATGATCCTCCATTTGGCTCATATGTAGTACCTATAACAGTGAGAGATAGACTTGGCATGTCTAGTGTCACTTCATTGGATGTTACACTGTGTGACTGCATTACCGAAAATGACTGCACACATCGTGTAGATCCAAGGATTGGCGGTGGAGGAGTACAACTTGGAAAGTGGGCCATCCTTGCAATATTGTTGGGCATAGCATTGCTCTTTTGCATCCTGTTTACGCTGGTCTGTGGGGCTTCTGGGACGTCTAAACAACCAAAAGTAATTCCTGATGATTTAGCCCAGC

product line

MISSION®

product line

MISSION®

product line

MISSION®

product line

MISSION®

Ensembl | human accession no.

ENSG00000134762

Ensembl | human accession no.

ENSG00000134765

Ensembl | human accession no.

ENSG00000116017

Ensembl | human accession no.

ENSG00000134755

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

NCBI accession no.

NM_001941

NCBI accession no.

NM_024421

NCBI accession no.

NM_005224

NCBI accession no.

NM_024422

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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    Svitlana Kurinna et al.
    Nature communications, 5, 5099-5099 (2014-10-07)
    The Nrf2 transcription factor controls the expression of genes involved in the antioxidant defense system. Here, we identified Nrf2 as a novel regulator of desmosomes in the epidermis through the regulation of microRNAs. On Nrf2 activation, expression of miR-29a and

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