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EHU068161

Sigma-Aldrich

MISSION® esiRNA

targeting human CD47

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1 EA
CN¥3,030.07

CN¥3,030.07

Estimated to ship onJune 03, 2025Details

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1 EA
CN¥3,030.07

About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

CN¥3,030.07

Estimated to ship onJune 03, 2025Details

description

Powered by Eupheria Biotech

Quality Level

100

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

GGCCTCTGGCCTCTAGGTAACCAGTTTAAATTGGTTCAGGGTGATAACTACTTAGCACTGCCCTGGTGATTACCCAGAGATATCTATGAAAACCAGTGGCTTCCATCAAACCTTTGCCAACTCAGGTTCACAGCAGCTTTGGGCAGTTATGGCAGTATGGCATTAGCTGAGAGGTGTCTGCCACTTCTGGGTCAATGGAATAATAAATTAAGTACAGGCAGGAATTTGGTTGGGAGCATCTTGTATGATCTCCGTATGATGTGATATTGATGGAGATAGTGGTCCTCATTCTTGGGGGTTGCCATTCCCACATTCCCCCTTCAACAAACAGTGTAACAGGTCCTTCCCAGATTTAGGGTACTTTTATTGATGGATATGTTTTCCTTTTATTCACATAACCCCTTGAAACCCTG

Ensembl | human accession no.

ENSG00000196776

NCBI accession no.

NM_198793

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... CD47(961) , CD47(961)

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铂 wire reel, 2m, diameter 0.08mm, hard, 99.9%

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铂 wire reel, 2m, diameter 0.063mm, hard, 99.9%

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铂 wire reel, 2m, diameter 0.25mm, hard, 99.95%

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铂 wire reel, 2m, diameter 0.05mm, hard, 99.99%

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manufacturer/tradename

Goodfellow 748-913-02

manufacturer/tradename

Goodfellow 049-732-49

manufacturer/tradename

Goodfellow 952-337-10

manufacturer/tradename

Goodfellow 731-337-48

assay

99.9%

assay

99.9%

assay

≥99.95%

assay

99.99%

resistivity

10.6 μΩ-cm, 20°C

resistivity

10.6 μΩ-cm, 20°C

resistivity

10.6 μΩ-cm, 20°C

resistivity

10.6 μΩ-cm, 20°C

bp

3827 °C (lit.)

bp

3827 °C (lit.)

bp

3827 °C (lit.)

bp

3827 °C (lit.)

density

21.45 g/cm3 (lit.)

density

21.45 g/cm3 (lit.)

density

21.45 g/cm3 (lit.)

density

21.45 g/cm3 (lit.)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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    Xuejian Liu et al.
    Oncology research, 27(4), 415-422 (2018-01-13)
    Cluster of differentiation 47 (CD47) overexpression is common in various malignancies. This study investigated whether CD47 promotes human glioblastoma invasion and, if so, the underlying mechanisms involved. CD47 expression was found to be stronger in tissues of patients with glioblastoma
    Xifu Song et al.
    Experimental and therapeutic medicine, 20(4), 3301-3309 (2020-08-29)
    Treatment with cluster of differentiation 47 (CD47) monoclonal antibody has exhibited promising antitumor effects in various preclinical cancer models. However, its role in pancreatic ductal adenocarcinoma (PDAC) remains unclear. In the present study, the CD47 expression level was measured in
    Natasha M Rogers et al.
    Kidney international, 90(2), 334-347 (2016-06-05)
    Defects in renal tubular epithelial cell repair contribute to renal ischemia reperfusion injury, cause acute kidney damage, and promote chronic renal disease. The matricellular protein thrombospondin-1 and its receptor CD47 are involved in experimental renal ischemia reperfusion injury, although the
    Hui Zhao et al.
    Scientific reports, 6, 29719-29719 (2016-07-15)
    CD47 is overexpressed in many human cancers, its level positively correlates with tumor invasion and metastasis. However, it is largely unknown whether CD47 overexpression drives metastasis and how CD47 lead to tumor metastasis in non-small cell lung cancer (NSCLC). In
    Jing Li et al.
    Experimental cell research, 388(1), 111811-111811 (2020-01-04)
    Age-related macular degeneration is a progressive ocular disease that is the leading cause of vision loss among elderly. AMD usually is divided into two types: wet and dry AMD, which is linked with inflammation. Choroidal Neovascularization (CNV) formation or wet
    View All Related Papers

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