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EHU012961

Sigma-Aldrich

MISSION® esiRNA

targeting human TCEAL1

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UNSPSC Code:
41105324
NACRES:
NA.51

description

Powered by Eupheria Biotech

Quality Level

100

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

GCAGCCTCCTTGTGGAGTAGGAAAACATAAGCTTGAAGAAGGAAGCTTTAAAGAAAGGTTGGCTCGTTCTCGCCCGCAATTTAGAGGGGACATACATGGCAGAAATTTAAGCAATGAGGAGATGATACAGGCAGCAGATGAGCTAGAAGAGATGAAAAGAGTAAGAAACAAACTGATGATAATGCACTGGAAGGCAAAACGGAGCCGTCCTTATCCTATTTAATGTGTTCGGCCTTTAATTCTGTTTTGCCTGCTAATAGTATTGCCATTGCCACCTGGACTTTCTGTTTGCATTTTCTTAATGCCTTTTCCCATATTCTGAATTTTAACTTTTTGTGAGGCTTTATTTTAGATGTTTAGCATGTAACTCGCTTAAAGTTGAGGTTTCCCCCTAAAATCTACAAGTTTCCCTCTTTCAGTCATGAGCCC

Ensembl | human accession no.

ENSG00000172465

NCBI accession no.

NM_001006639
NM_001006640
NM_004780

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... TCEAL1(9338) , TCEAL1(9338)

Related Categories

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Anna E Vilgelm et al.
EBioMedicine, 24, 43-55 (2017-10-17)
Antagonists of MDM2-p53 interaction are emerging anti-cancer drugs utilized in clinical trials for malignancies that rarely mutate p53, including melanoma. We discovered that MDM2-p53 antagonists protect DNA from drug-induced damage in melanoma cells and patient-derived xenografts. Among the tested DNA

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