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Merck
CN

E8886

Erythrosin extra bluish

Dye content, ≥80%, certified by the Biological Stain Commission, powder

Synonym(s):

2′,4′,5′,7′-Tetraiodofluorescein disodium salt, Acid Red 51, Iodoeosin

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About This Item

Empirical Formula (Hill Notation):
C20H6I4Na2O5
CAS Number:
16423-68-0
Molecular Weight:
879.86
Colour Index Number:
45430
Beilstein:
1443945
EC Number:
240-474-8
MDL number:
MFCD00144257
UNSPSC Code:
12171500
PubChem Substance ID:
24894685
NACRES:
NA.47

Key Documents

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Product Name

Erythrosin extra bluish, certified by the BSC

Agency

certified by the BSC

Quality Level

200

form

powder

composition

Dye content, ≥80%

pH

6.4 (30.3 °C)

mp

315 °C

solubility

water: 1 mg/mL, clear

density

0.625-0.731 g/cm3 at 30.1 °C

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

[Na+].[Na+].[O-]c1c(I)cc2c(Oc3c(I)c([O-])c(I)cc3C24OC(=O)c5ccccc45)c1I

InChI

1S/C20H8I4O5.2Na/c21-11-5-9-17(13(23)15(11)25)28-18-10(6-12(22)16(26)14(18)24)20(9)8-4-2-1-3-7(8)19(27)29-20;;/h1-6,25-26H;;/q;2*+1/p-2

InChI key

RAGZEDHHTPQLAI-UHFFFAOYSA-L

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General description

Erythrosin extra bluish is soluble in ethanol and water. It is a brown powder, with a pH range of 2.5 to 4. It is used in color filters, light emitting diodes, cosmetics and hair dyes. It has been used in many biological applications such as, detecting gene expression, treating age related macular degeneration, diabetes and obesity.

Application

Certified for use in the Jackson stain for plant anatomy; counterstain for alum hematoxylin; Kreyberg′s method for keratin and mucus.

Pictograms

Exclamation markEnvironment
GHS07,GHS09

Signal Word

Warning

Hazard Statements

H302,H411

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

359.6 °F - closed cup

Flash Point(C)

182 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
SHBR6554
0000244685
0000244685
SHBQ3587
SHBN5588

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R W Sabnis.
Handbook of Acid-Base Indicators (2007)
R W Sabnis.
Handbook of Biological Dyes and Stains: Synthesis and Industrial Applications, 544-544 (2010)
Ying-Ju Huang et al.
ChemMedChem, 7(4), 571-577 (2012-02-23)
SecA is a central component of the general secretion system that is essential for bacterial growth and thus an ideal target for antimicrobial agents. A series of fluorescein analogues were first screened against the ATPase activity using the truncated unregulated
Anna Carolina Borges Pereira Costa et al.
Archives of oral biology, 56(11), 1299-1305 (2011-06-28)
The effect of erythrosine- and LED-mediated photodynamic therapy (PDT) on planktonic cultures and biofilms of Candida albicans and Candida dubliniensis was evaluated. Planktonic cultures of standardized suspensions (10(6)cells/mL) of C. albicans and C. dubliniensis were treated with erythrosine concentrations of
Chueh-Pin Chen et al.
Photochemistry and photobiology, 88(3), 570-576 (2012-01-31)
The growing resistance to antibiotics has rendered antimicrobial photodynamic inactivation (PDI) an attractive alternative treatment modality for infectious diseases. Chitosan (CS) was shown to further potentiate the PDI effect of photosensitizers and was therefore used in this study to investigate
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