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Safety Information

E8004

Sigma-Aldrich

β-Estradiol 17-cypionate

Synonym(s):

1,3,5(10)-Estratriene-3,17β-diol 17-cyclopentylpropionate, 3,17β-Hydroxy-1,3,5(10)-estratriene 17-cyclopentylpropionate, Depoestradiol

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About This Item

Empirical Formula (Hill Notation):
C26H36O3
CAS Number:
313-06-4
Molecular Weight:
396.56
EC Number:
206-237-8
MDL number:
MFCD00056558
UNSPSC Code:
12352200
PubChem Substance ID:
24894663
NACRES:
NA.77

biological source

synthetic (organic)

Quality Level

100

sterility

non-sterile

Assay

≥98% (HPLC)

form

powder

solubility

chloroform: 50 mg/mL, clear, colorless to faintly yellow

shipped in

ambient

storage temp.

room temp

SMILES string

[H][C@]12CC[C@]3(C)[C@H](CC[C@@]3([H])[C@]1([H])CCc4cc(O)ccc24)OC(=O)CCC5CCCC5

InChI

1S/C26H36O3/c1-26-15-14-21-20-10-8-19(27)16-18(20)7-9-22(21)23(26)11-12-24(26)29-25(28)13-6-17-4-2-3-5-17/h8,10,16-17,21-24,27H,2-7,9,11-15H2,1H3/t21-,22-,23+,24+,26+/m1/s1

InChI key

UOACKFBJUYNSLK-XRKIENNPSA-N

Gene Information

human ... ESR1(2099)

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Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Repr. 1B

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
MKCW1862
MKCR8411
MKCM8064
MKCL3909
MKCC4090

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Ocilon Gomes Sá Filho et al.
Animal reproduction science, 112(1-2), 95-106 (2008-05-13)
Three experiments evaluated effects of estradiol (E(2)) and/or progesterone (P(4)) prior to induction of ovulation with GnRH on subsequent luteal lifespan in anestrous Nelore cows. In Experiment 1, cows (25-65 days post-partum [DPP]; n=114) were assigned randomly to receive a
G M Tiboni et al.
Human reproduction (Oxford, England), 24(11), 2688-2692 (2009-07-30)
The aromatase inhibitor, letrozole, exerts embryo toxic effects in rats, causing increased embryo lethality and anomalies of the axial skeleton at pharmacologically relevant doses. Letrozole acts by inhibiting estrogen biosynthesis. It may thus be feasible that estrogen deprivation is a
A H Souza et al.
Theriogenology, 72(1), 10-21 (2009-03-10)
The objectives were to evaluate the effects of equine chorionic gonadotropin (eCG) supplementation (with or without eCG) and type of ovulatory stimulus (GnRH or ECP) on ovarian follicular dynamics, luteal function, and pregnancies per AI (P/AI) in Holstein cows receiving
A D P Rodrigues et al.
Theriogenology, 79(1), 135-141 (2012-11-06)
Four experiments were conducted to evaluate hormonal strategies to induce ovulation in Nellore heifers. In experiment 1, heifers (N = 1039) received a controlled internal drug release (CIDR) of fourth use (CIDR-4) on Day -12 or no CIDR (CIDR-0). The
J Hillegass et al.
Journal of dairy science, 91(11), 4226-4237 (2008-10-24)
Our objectives were to compare reproductive responses of dairy cows receiving timed artificial insemination (AI) either at 48 or 72 h after induction of luteolysis and supplemented or not with estradiol cypionate (ECP). Holstein cows (971) had their estrous cycles
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