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E6635

Sigma-Aldrich

Ethylenediaminetetraacetic acid disodium salt dihydrate

Sigma Grade, suitable for plant cell culture, 98.5-101.5%

Synonym(s):

Disodium ethylenediaminetetraacetate dihydrate, EDTA disodium salt, EDTA-Na2, Edathamil, Edetate disodium salt dihydrate, Sequestrene Na2

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100 G
¥980.32
500 G
¥881.77
1 KG
¥1,593.12

¥980.32

Available to ship on2025年4月10日Details

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100 G
¥980.32
500 G
¥881.77
1 KG
¥1,593.12

About This Item

Empirical Formula (Hill Notation):
C10H14N2Na2O8 · 2H2O
CAS Number:
6381-92-6
Molecular Weight:
372.24
Beilstein:
3900609
EC Number:
205-358-3
UNSPSC Code:
12352107
PubChem Substance ID:
24894632
NACRES:
NA.77

¥980.32

Available to ship on2025年4月10日Details

Request a Bulk Order

grade

Sigma Grade

Assay

98.5-101.5%

form

powder

reaction suitability

reagent type: chelator

technique(s)

cell culture | plant: suitable

mp

248 °C (dec.) (lit.)

solubility

H2O: soluble, clear, colorless

SMILES string

O.O.O.O.[Na+].[Na+].[Na+].[Na+].OC(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC(O)=O.OC(=O)CN(CCN(CC(O)=O)CC([O-])=O)CC([O-])=O

InChI

1S/C10H16N2O8.2Na.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;2*1H2/q;2*+1;;/p-2

InChI key

OVBJJZOQPCKUOR-UHFFFAOYSA-L

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This Item
E5134ED2SS27285
乙二胺四乙酸 二钠盐 二水合物 Sigma Grade, suitable for plant cell culture, 98.5-101.5%

E6635

乙二胺四乙酸 二钠盐 二水合物

乙二胺四乙酸 二钠盐 二水合物 suitable for electrophoresis, for molecular biology, 99.0-101.0% (titration)

E5134

乙二胺四乙酸 二钠盐 二水合物

乙二胺四乙酸 二钠盐 二水合物 reagent grade, 98.5-101.5% (titration)

ED2SS

乙二胺四乙酸 二钠盐 二水合物

乙二胺四乙酸 二钠盐 二水合物 meets analytical specification of Ph. Eur., BP, USP, FCC, 99.0-101.0%

27285

乙二胺四乙酸 二钠盐 二水合物

grade

Sigma Grade

grade

for molecular biology

grade

reagent grade

grade

-

assay

98.5-101.5%

assay

99.0-101.0% (titration)

assay

98.5-101.5% (titration)

assay

99.0-101.0%

Quality Level

200

Quality Level

300

Quality Level

200

Quality Level

200

mp

248 °C (dec.) (lit.)

mp

248 °C (dec.) (lit.)

mp

248 °C (dec.) (lit.)

mp

248 °C (dec.) (lit.)

solubility

H2O: soluble, clear, colorless

solubility

3  M NaOH: 1.6 g/10 mL

solubility

H2O: soluble, clear, colorless

solubility

water: soluble 100 g/L at 20 °C

General description

Ethylenediaminetetraacetic acid (EDTA) is an aminopolycarboxylic acid and a hexadentate ligand. It chelates with metal ions, especially with cations to form an octahedral complex.[1] Ethylenediaminetetraacetic acid disodium salt (EDTA) is a blood anticoagulant and contributes to the pathogenesis of pseudothrombocytopenia. It chelates with calcium in the blood and inhibits clotting and is routinely used in haematological tests.[2] It enhances the antibacterial activity of lysozyme.[3] EDTA used in chelation therapy chelates with calcium and favors dilation of artery, solubilisation of atheromatous plaques in atherosclerotic vascular disease.[4] EDTA chelation therapy may also protect from oxidative damage during blood and lipid peroxidation in liver fibrosis. [5]

Application

Chelator of divalent cations. Inhibits enzymes, such as metalloproteases, that require divalent cations for activity.
Ethylenediaminetetraacetic acid disodium salt dihydrate has been in seed germination trials of plant species[6] and in protein extraction from Moss, Physcomitrella paten.[7] It has also been used in lysis and vacuole buffer for the isolation of vacuoles from Petunia petals.[8]

Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Warning

Hazard Statements

H332,H373

Hazard Classifications

Acute Tox. 4 Inhalation - STOT RE 2 Inhalation

Target Organs

Respiratory Tract

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves
  • Specification Sheet

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    Certificates of Analysis (COA)

    Lot/Batch Number
    0000352602
    0000316928
    0000316929
    0000316930
    0000316930

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    Isolation of Intact Vacuoles from Petunia Petals and Extraction of Sequestered Glycosylated Phenylpropanoid Compounds
    Skaliter O, et al.
    Bio-protocol, 8(13), 56-56 (2017)
    Induced Plant Accumulation of Lithium
    Kavanagh L, et al.
    Geostandards Newsletter, 8(2), 56-56 (2018)
    A Phosphopeptide Purification Protocol for the Moss Physcomitrella paten
    Wang, X and He Y
    Bio-protocol, 5(14), 56-56 (2015)
    EDTA chelation therapy for cardiovascular disease: a systematic review
    Seely DMR, et al.
    BMC Cardiovascular Disorders, 5(1), 32-32 (2005)
    Ethylenediaminetetraacetic acid induces antioxidant and anti-inflammatory activities in experimental liver fibrosis
    Gonzalez-Cuevas J, et al.
    Redox Report, 16(2), 62-70 (2011)
    View All Related Papers

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