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Key Documents

Safety Information

E6507

Sigma-Aldrich

β-Estradiol 6-(O-carboxy­methyl)oxime: BSA fluorescein iso­thio­cyanate conjugate

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About This Item

MDL number:
MFCD00133133
UNSPSC Code:
12352202
NACRES:
NA.77

form

lyophilized powder

Quality Level

200

extent of labeling

3-5 mol FITC per mol BSA
5-10 mol steroid per mol BSA

solubility

0.1 M phosphate buffer: 0.98-1.02 mg/mL, clear, yellow to orange (pH: 7.5)

shipped in

ambient

storage temp.

2-8°C

SMILES string

S=C=Nc5c6c(ccc5O)C8(OC(=O)c9c8cccc9)c7c(cc(cc7)O)O6.N(OCC(=O)O)C1=C[C@H]2[C@H]3[C@@]([C@H](CC3)O)(CC[C@@H]2c4c1cc(cc4)O)C

InChI key

DZYKSUALQNKEPM-TUXUTZNTSA-N

Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Warning

Hazard Statements

H302 + H312 + H332,H351

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

监管及禁止进口产品

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Certificates of Analysis (COA)

Lot/Batch Number
13110614
042M4042V
079K4164
077K4015
035K4111

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Yu Pan et al.
Hormones & cancer, 11(2), 87-96 (2020-02-11)
Proline-, glutamic acid-, leucine-rich protein 1 (PELP1) is a novel estrogen receptor (ER) coregulator, demonstrated distinctive characters from other ERα coregulators, and has been suggested to be involved in metastasis of several cancers. In ERα-positive breast cancer, PELP1 overexpression enhanced
Synthesis of fluorescein labelled steroid hormone-albumin conjugates for the fluorescent histochemical detection of hormone receptors.
E Gaetjens et al.
Journal of steroid biochemistry, 13(8), 1001-1003 (1980-08-01)

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