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E4504

Sigma-Aldrich

cis-8,11,14-Eicosatrienoic acid

≥99%

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Synonym(s):
bis-Homo-γ-linolenic acid, Homo-γ-linolenic acid
Linear Formula:
CH3(CH2)3(CH2CH=CH)3(CH2)6CO2H
CAS Number:
Molecular Weight:
306.48
Beilstein:
1796533
EC Number:
MDL number:
UNSPSC Code:
12352211
PubChem Substance ID:
NACRES:
NA.25

biological source

plant oil (Borage)

Quality Level

Assay

≥99%

form

viscous liquid

refractive index

n20/D 1.478 (lit.)

functional group

carboxylic acid

lipid type

omega FAs

shipped in

ambient

storage temp.

−20°C

SMILES string

CCCCC\C=C/C\C=C/C\C=C/CCCCCCC(O)=O

InChI

1S/C20H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13H,2-5,8,11,14-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-

InChI key

HOBAELRKJCKHQD-QNEBEIHSSA-N

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Related Categories

WGK

WGK 3

Flash Point(F)

143.6 °F

Flash Point(C)

62 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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R M Hamilton et al.
Lipids, 16(5), 374-376 (1981-05-01)
Possible relationships between zinc and essential fatty acid metabolism have been assessed using plasma samples obtained from 39 cystic fibrosis patients. The fatty acid composition of plasma phospholipids was analyzed by capillary gas liquid chromatography and zinc levels were measured
C Thijs et al.
European journal of clinical nutrition, 54(3), 234-238 (2000-03-14)
To evaluate whether levels of n-6 long chain polyunsaturated fatty acids (LCPs) in human breast milk are related to the mother's atopic constitution, and whether a decreased level can be restored by gamma-linolenic acid supplementation. Cross-sectional study and dietary supplementation
R D Abraham et al.
Atherosclerosis, 81(3), 199-208 (1990-04-01)
Low levels of essential polyunsaturated fatty acids of the n-6 series are associated with coronary heart disease. Linoleic acid, but not gamma-linolenic acid requires the activity of delta 6-desaturase for its conversion to dihomo-gamma-linolenic and arachidonic acid. Evening primrose oil
B C Melnik et al.
Journal of the American Academy of Dermatology, 21(3 Pt 1), 557-563 (1989-09-01)
Our hypothesis on the origin of atopy links alterations in omega-6-fatty acid metabolism in atopic persons (i.e., reduced formation of delta-6-desaturase products) to deficient T cell differentiation and function. We suggest that a relative deficiency in dihomo-gamma-linolenic acid-derived prostaglandin E1
Minho Kim et al.
International journal of medical sciences, 17(5), 626-631 (2020-03-27)
Keratinocyte proliferation is important for skin wound healing. The wound healing process includes blood clotting around the wound, removal of dead cells and pathogens through inflammation, and then re-epithelialization through proliferation and maturation. Proliferation assay was performed on acid natural

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