E1904
Ethyl-3,4-dephostatin
>99% (HPLC), solid
Synonym(s):
3,4-Dihydroxy-N-ethyl-N-nitrosoaniline
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About This Item
Empirical Formula (Hill Notation):
C8H10N2O3
CAS Number:
Molecular Weight:
182.18
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Product Name
Ethyl-3,4-dephostatin, >99% (HPLC), solid
InChI key
ZTXUSFPBLYQDDN-UHFFFAOYSA-N
SMILES string
CCN(N=O)c1ccc(O)c(O)c1
InChI
1S/C8H10N2O3/c1-2-10(9-13)6-3-4-7(11)8(12)5-6/h3-5,11-12H,2H2,1H3
assay
>99% (HPLC)
form
solid
color
brown
solubility
DMSO: soluble 22 mg/mL
H2O: soluble 8 mg/mL
storage temp.
2-8°C
Quality Level
Related Categories
Biochem/physiol Actions
Stable analog of dephostatin. Selective inhibitor of protein tyrosine phosphatase 1B and SHPTP-1. Does not inhibit CD45-associated phosphatases.
Disclaimer
Store under nitrogen
Features and Benefits
This compound is featured on the Phosphoprotein Phosphatases (Tyrosine) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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J H Kim et al.
Cell death & disease, 4, e588-e588 (2013-04-13)
Hypoxia enhances the proliferation and migration of adipose-derived stem cells (ASCs) via the generation of reactive oxygen species (ROS). Therefore, this study primarily investigated whether or not ROS generation could regulate microRNA-210 (miR-210) expression, and increase proliferation/migration of ASCs. In
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