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Merck
CN

D9885

DEAE-Dextran hydrochloride

powder

Synonym(s):

Diethylaminoethyl-dextran hydrochloride

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About This Item

CAS Number:
UNSPSC Code:
12352201
NACRES:
NA.25
MDL number:
Technical Service
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biological source

bacterial (Leuconostoc mesenteroides)

Quality Level

form

powder

extent of labeling

~3.2% nitrogen

useful pH range

4.0 - 6.0

solubility

H2O: soluble 100 mg/mL, clear, colorless to faintly yellow

storage temp.

room temp

Application

DEAE-Dextran 500, a polycationic stabilizing molecule and transfection reagent, is used in the development of sustained release protein delivery and nucleic acid transfection systems. DEAE-Dextran 500 may be used for cell immobilization in biosensors.

Other Notes

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Articles

Discover the role of carbohydrates in drug delivery, from solubility and stability improvement to advanced controlled-release systems.

Explore how carbohydrates function as excipients and carriers in drug delivery, with insights into mechanisms, case studies, and future trends.

Related Content

Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, featuring a linear backbone of α-linked d-glucopyranosyl repeating units.


Transfection using DEAE-dextran.
Selden RF.
Current Protocols in Immunology, 10, 10-10 (2001)
DEAE-dextran transfection of mammalian cultured cells.
E T Schenborn et al.
Methods in molecular biology (Clifton, N.J.), 130, 147-153 (1999-12-10)
Bhawna Yadav et al.
Cell surface (Amsterdam, Netherlands), 6, 100042-100042 (2020-12-29)
We designed experiments to assess whether fungal cell wall mannans function as an immune shield or an immune agonist. Fungal cell wall β-(1,3)-glucan normally plays a major and dominant role in immune activation. The outer mannan layer has been variously



Global Trade Item Number

SKUGTIN
D9885-50G04061833033265
D9885-100G04061833591277
D9885-10G04061833591284