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D5764

Sigma-Aldrich

2,3-Diphospho-D-glyceric acid pentasodium salt

glycolysis metabolite

Synonym(s):

2,3-DPG, D-Glycerate 2,3-diphosphate sodium salt

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About This Item

Linear Formula:
C3H3O10P2Na5
CAS Number:
102783-53-9
Molecular Weight:
375.95
MDL number:
MFCD00070074
UNSPSC Code:
12352201
PubChem Substance ID:
24893967
NACRES:
NA.25

biological source

synthetic

form

powder

impurities

3-phosphoglyceric acid, essentially free

color

white to off-white

solubility

water: 100 mg/mL, clear, colorless to faintly yellow

cation traces

Na: 24.5-32.5% (anhydrous)

storage temp.

−20°C

SMILES string

[Na].OC(=O)[C@@H](COP(O)(O)=O)OP(O)(O)=O

InChI

1S/C3H8O10P2.Na.H/c4-3(5)2(13-15(9,10)11)1-12-14(6,7)8;;/h2H,1H2,(H,4,5)(H2,6,7,8)(H2,9,10,11);;/t2-;;/m1../s1

InChI key

JJEMSNINYKJOBZ-YBBRRFGFSA-N

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SLB®-IL61 Capillary GC Column

matrix active group

Non-bonded; 1,12-Di(tripropylphosphonium)dodecane bis(trifluoromethanesulfonyl)imide phase

matrix active group

Non-bonded; 1,12-Di(tripropylphosphonium)dodecane bis(trifluoromethanesulfonyl)imide phase

matrix active group

Non-bonded; 1,12-Di(2,3-dimethylimidazolium)dodecane bis(trifluoromethanesulfonyl)imide phase

matrix active group

Non-bonded; 1,12-Di(tripropylphosphonium)dodecane bis(trifluoromethanesulfonyl)imide trifluoromethanesulfonate phase

parameter

≤25-300 °C temperature (isothermal or programmed)

parameter

≤25-300 °C temperature (isothermal or programmed)

parameter

50-270 °C temperature (isothermal or programmed)

parameter

40-290 °C temperature (isothermal or programmed)

application(s)

agriculture
chemicals and industrial polymers
clinical
environmental
food and beverages
forensics and toxicology
petroleum

application(s)

agriculture
chemicals and industrial polymers
clinical
environmental
food and beverages
forensics and toxicology
petroleum

application(s)

environmental

application(s)

-

technique(s)

gas chromatography (GC): suitable (fast GC)

technique(s)

gas chromatography (GC): suitable

technique(s)

gas chromatography (GC): suitable

technique(s)

gas chromatography (GC): suitable (fast GC)

material

fused silica

material

fused silica

material

fused silica

material

fused silica

Application

D-Glycerate 2,3-diphosphate, cofactor of both phosphoglyceric acid mutase and hemoglobin, may be used as a reference compound in analysis of blood cell (erythrocyte) glycolysic cycle metabolites.

Biochem/physiol Actions

Metabolite of glycolysis within human erythrocytes produced by 2,3-diphosphoglycerate mutase in an alternative to the glycolytic pathway. Binds to hemaglobin to reduce oxygenation.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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    Linda Larsson et al.
    Vox sanguinis, 116(1), 60-70 (2020-09-13)
    Commercial blood bags are predominantly made of polyvinyl chloride (PVC) plasticized with di(2-ethylhexyl) phthalate (DEHP). DEHP is favourable for storage of red blood cells (RBC). Historically, removal of DEHP from blood bags has been linked to unacceptable haemolysis levels. Oncoming
    Yueqi Zhao et al.
    Science advances, 6(12), eaaw9679-eaaw9679 (2020-03-29)
    Rhesus D (RhD) is one of the most important immunogenic antigens on red blood cells (RBCs). However, the supply of RhD-negative blood frequently faces critical shortages in clinical practice, and the positive-to-negative transition of the RhD antigen remains a great
    Ida Stangerup et al.
    Transfusion, 57(8), 1905-1911 (2017-04-30)
    No former studies have examined how blood donation influences physical performance in women, who due to menstruation may have a slower recovery of performance. Therefore, the aim of this study was to clarify how VO VO VO VO
    H Gulliksson et al.
    Vox sanguinis, 112(1), 33-39 (2016-12-22)
    The present general plasticizer di-2-ethylhexyl-phthalate in polyvinylchloride (PVC) blood bags is only physically dispersed in PVC and will therefore leach into blood components. The objective of this study was to perform a first preliminary red blood cell (RBC) storage evaluation
    Manon Bardyn et al.
    Metabolites, 10(6) (2020-06-04)
    After blood donation, the red blood cells (RBCs) for transfusion are generally isolated by centrifugation and then filtrated and supplemented with additive solution. The consecutive changes of the extracellular environment participate to the occurrence of storage lesions. In this study
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