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D5520

Sigma-Aldrich

Dimethyl dicarbonate

for histidine methylation

Synonym(s):

DMPC, Dimethyl pyrocarbonate, Pyrocarbonic acid dimethyl ester

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About This Item

Linear Formula:
(CH3OCO)2O
CAS Number:
Molecular Weight:
134.09
Beilstein:
956715
EC Number:
MDL number:
UNSPSC Code:
12352202
PubChem Substance ID:

biological source

synthetic

form

liquid

refractive index

n20/D 1.392 (lit.)

bp

45-46 °C/5 mmHg (lit.)

density

1.25 g/mL at 25 °C (lit.)

storage temp.

room temp

SMILES string

COC(=O)OC(=O)OC

InChI

1S/C4H6O5/c1-7-3(5)9-4(6)8-2/h1-2H3

InChI key

GZDFHIJNHHMENY-UHFFFAOYSA-N

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Application

Methylates one or two histidine residues at the active site of PEP carboxykinase; the resulting inhibition is only partially reversible.

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Pictograms

Skull and crossbonesCorrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

185.0 °F

Flash Point(C)

85 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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