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Merck
CN

D4266

3-(Decyldimethylammonio)­propane­sulfonate inner salt

zwitterionic detergent

Synonym(s):

Caprylyl sulfobetaine, SB3-10

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About This Item

Linear Formula:
CH3(CH2)9N+(CH3)2CH2CH2CH2SO3-
CAS Number:
15163-36-7
Molecular Weight:
307.49
UNSPSC Code:
12161900
NACRES:
NA.25
PubChem Substance ID:
24893849
MDL number:
MFCD00036908
Beilstein/REAXYS Number:
3967284

Key Documents

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Product Name

3-(Decyldimethylammonio)­propane­sulfonate inner salt, zwitterionic detergent

InChI

1S/C15H33NO3S/c1-4-5-6-7-8-9-10-11-13-16(2,3)14-12-15-20(17,18)19/h4-15H2,1-3H3

SMILES string

CCCCCCCCCC[N+](C)(C)CCCS([O-])(=O)=O

InChI key

WKALLSVICJPZTM-UHFFFAOYSA-N

assay

≥98.0% (TLC)

form

powder

mol wt

micellar avg mol wt 12,600

aggregation number

41

technique(s)

enzyme immunoassay: suitable
protein purification: suitable
protein quantification: suitable

conductivity

<20 μmho per cm at 24 °C (0.1 M aqueous solution)

CMC

25-40 mM (20-25°C)

Quality Level

200

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Application

3-(Decyldimethylammonio)­propane­sulfonate inner salt was used:
  • In a study to demonstrate a polyurethane chip that electrostatically binds to immunoglobulin G (IgG).
  • In a study to describe a method for isolating a high yield of Arabidopsis chloroplasts.
  • Solubilization of oleosins.
Zwitterionic detergent used for protein solubilization.

General description

3-(Decyldimethylammonio)­propane­sulfonate inner salt, a zwitterionic surfactant, is a sulfobetaine. Sulfobetaines contain a positively charged quaternary ammonium group and a negatively charged sulfonic group.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000509937
0000509937
0000497611
0000497611
0000392374

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Effects of long-chains of zwitterionic micelles on binding constants of triflusal and acetylsalicylic acid.
Ferrit M, et al.
Colloids and Surfaces. A, Physicochemical and Engineering Aspects, 345(1), 26-30 (2009)
Synthesis and surface-active properties of sulfobetaine-type zwitterionic gemini surfactants.
Yoshimura T, et al.
Colloids and Surfaces. A, Physicochemical and Engineering Aspects, 273(1), 208-212 (2006)
Solubilization conditions for hydrophobic membrane protein, oleosin, in soybeans
Kim, H., et al.
Biotechnology and Bioprocess Engineering: BBE, 12, 542-542 (2007)
L I Hochstein et al.
Biochemical and biophysical research communications, 147(1), 295-300 (1987-08-31)
A membrane-bound ATPase from Halobacterium saccharovorum was solubilized using sodium deoxycholate and Zwittergent 3-10 and purified by hydrophobic and ammonium sulfate-mediated chromatography. The enzyme, which had a molecular mass of 350 kDa, was composed of two major (87 and 60
Kenji Murakami et al.
The Journal of biological chemistry, 288(9), 6325-6332 (2013-01-11)
Whereas individual RNA polymerase II (pol II)-general transcription factor (GTF) complexes are unstable, an assembly of pol II with six GTFs and promoter DNA could be isolated in abundant homogeneous form. The resulting complete pol II transcription preinitiation complex (PIC)
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