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Key Documents

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Safety Information

D4072

Sigma-Aldrich

Delta Sleep Inducing Peptide

Synonym(s):

DSIP, Emideltide, Sleep inducing peptide, Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu

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1 G
CN¥1,464.20

CN¥1,464.20

Available to ship onApril 23, 2025Details

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1 G
CN¥1,464.20

About This Item

Empirical Formula (Hill Notation):
C35H48N10O15
CAS Number:
62568-57-4
Molecular Weight:
848.81
MDL number:
MFCD00076883
UNSPSC Code:
12352200
PubChem Substance ID:
329798794
NACRES:
NA.32

CN¥1,464.20

Available to ship onApril 23, 2025Details

Request a Bulk Order

form

powder

storage temp.

−20°C

SMILES string

C[C@H](NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)NCC(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(O)=O

InChI

1S/C35H48N10O15/c1-16(41-32(56)20(36)9-18-11-37-21-6-4-3-5-19(18)21)30(54)39-12-25(47)38-13-26(48)44-23(10-29(52)53)34(58)42-17(2)31(55)45-24(15-46)33(57)40-14-27(49)43-22(35(59)60)7-8-28(50)51/h3-6,11,16-17,20,22-24,37,46H,7-10,12-15,36H2,1-2H3,(H,38,47)(H,39,54)(H,40,57)(H,41,56)(H,42,58)(H,43,49)(H,44,48)(H,45,55)(H,50,51)(H,52,53)(H,59,60)/t16-,17-,20-,22-,23-,24-/m0/s1

InChI key

ZRZROXNBKJAOKB-GFVHOAGBSA-N

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Show Differences

1 of 4

This Item
404308552047848
Potassium sorbate Pharmaceutical Secondary Standard; Certified Reference Material

PHR1278

Potassium sorbate

Potassium sorbate certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

40430

Potassium sorbate

Potassium sorbate purum p.a., ≥99.0% (NT)

85520

Potassium sorbate

Potassium Sorbate analytical standard

47848

Potassium Sorbate

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

Quality Level

300

Quality Level

300

Quality Level

200

Quality Level

100

grade

certified reference material, pharmaceutical secondary standard

grade

certified reference material, TraceCERT®

grade

-

grade

analytical standard

storage temp.

2-30°C

storage temp.

-

storage temp.

-

storage temp.

2-30°C

agency

traceable to Ph. Eur. P2650000

agency

-

agency

-

agency

-

Amino Acid Sequence

Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu-OH

General description

Delta sleep inducing peptide (DSIP) is a nonapeptide which was isolated from the rabbit brain. It is synthesized in the hypothalamus and is present in small amounts in the blood.

Biochem/physiol Actions

DSIP promotes sleep by targeting various areas of the brain. The peptide is easily absorbed from the gut and is not denatured by enzymes. It crosses the blood-brain barrier easily. DSIP influences the circadian rhythm in humans. Low concentrations of the peptide are observed in patients with schizophrenia and depression.[1]

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

监管及禁止进口产品

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    SLBK6162

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    Delta sleep-inducing peptide
    Pollard BJ and Pomfrett CJD
    European Journal of Anaesthesiology, 18(7), 419-422 (2001)
    Joo Sung Kim et al.
    Macromolecular bioscience, 20(11), e2000147-e2000147 (2020-07-15)
    Mechanoreceptors in human skin possess high sensitivity, wide sensing range, and high sensing resolution for external stimuli. Several attempts have been made to implement electronic skin (e-skin) that can mimic human skin. However, previous attempts are limited by the fundamental
    Piia Liigand et al.
    Journal of mass spectrometry : JMS, 54(6), 481-487 (2019-03-09)
    Electrospray ionization is widely used to generate gas phase ions from a variety of molecules ranging from small ions to large proteins, while the ionization mechanism is claimed to depend on the size of the molecule. For small molecules, the

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