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Merck
CN

D3664

Deoxyribonucleic acid sodium salt from calf thymus

suitable for substrate for DNase (Readily soluble)

Synonym(s):

CT-DNA, calf thymus DNA, DNA sodium salt from calf thymus, Thymonucleic acid sodium salt

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About This Item

CAS Number:
73049-39-5
UNSPSC Code:
41106305
eCl@ss:
32160414
NACRES:
NA.51
MDL number:
MFCD00130922
Form:
powder or crystals
Storage temp.:
2-8°C

Key Documents

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form

powder or crystals

suitability

suitable for substrate for DNase (Readily soluble)

storage temp.

2-8°C

Quality Level

200

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Application

Calf thymus DNA (CT-DNA) is a natural DNA widely used in studies of DNA binding anticancer agents and DNA binding agents that modulate DNA structure and function. Calf thymus DNA is also used in physicochemical studies of DNA behavior in solution.

Packaging

Preweighed vials prepared from D1501

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

低风险生物材料
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Certificates of Analysis (COA)

Lot/Batch Number
0000477987
0000477987
0000476266
0000476266
0000464684

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Abdollah Zakeri Siavashani et al.
Biomaterials science, 8(1), 148-162 (2019-10-31)
Implantation of temporary and permanent biomaterials in the body leads to a foreign body reaction (FBR), which may adversely affect tissue repair processes and functional integration of the biomaterial. However, modulation of the inflammatory response towards biomaterials can potentially enable
Xingyi Chen et al.
Molecular pharmaceutics, 16(6), 2690-2699 (2019-05-01)
The nucleotide-binding domain and leucine-rich repeat-containing family, pyrin domain-containing 3 (NLRP3) inflammasome is a key regulator of innate immune responses, and its aberrant activation is implicated in the pathogenesis of many diseases such as Alzheimer's disease and type 2 diabetes.
Kristin Grøsvik et al.
Frontiers in microbiology, 11, 263-263 (2020-03-12)
The cellular methyl donor S-adenosylmethionine (SAM) and other endo/exogenous agents methylate DNA bases non-enzymatically into products interfering with replication and transcription. An important product is 3-methyladenine (m3A), which in Escherichia coli is removed by m3A-DNA glycosylase I (Tag) and II
Claire L Camp et al.
Analytical and bioanalytical chemistry, 402(1), 367-372 (2011-08-31)
The determination of total deoxyribonucleic acid (DNA) concentration is of great importance in many biological and bio-medical analyses. The quantification of DNA is traditionally performed by UV spectroscopy; however the results can be affected greatly by the sample matrix. The
Farhad Ahmadi et al.
DNA and cell biology, 31(2), 259-268 (2011-08-25)
In this work, multispectroscopic atomic force microscopy and molecular modeling [ONIOM 2(B3LYP/6-31++G(d,p): Universal Force Field (UFF)) level] techniques were used to study the interaction between Calf-Thymus-DNA (CT-DNA) and pyriproxyfen (PYR) insecticide. The binding constant of PYR with double-strand deoxyribonucleic acid
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Protocols

Enzymatic Assay of Deoxyribonuclease I (EC 3.1.21.1)

To standardize a procedure for the enzymatic assay of Deoxyribonuclease I.

脱氧核糖核酸酶I(EC 3.1.21.1)的酶促测定

建立脱氧核糖核酸酶I酶促测定的标准化操作流程。

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Product Information Sheet - D3664

Product Information Sheet

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