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Merck
CN

D3415

Bisphenol A diglycidyl ether

viscous liquid, PPARγ inhibitor

Synonym(s):

BADGE, DGEBA, NSC 5022, 2,2-Bis[4-(glycidyloxy)phenyl]propane, 4,4′-Isopropylidenediphenol diglycidyl ether, D.E.R.™ 332

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About This Item

Empirical Formula (Hill Notation):
C21H24O4
CAS Number:
1675-54-3
Molecular Weight:
340.41
NACRES:
NA.77
PubChem Substance ID:
57654090
UNSPSC Code:
12352200
EC Number:
216-823-5
MDL number:
MFCD00080480
Beilstein/REAXYS Number:
299026

Key Documents

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Product Name

Bisphenol A diglycidyl ether,

InChI key

LCFVJGUPQDGYKZ-UHFFFAOYSA-N

InChI

1S/C21H24O4/c1-21(2,15-3-7-17(8-4-15)22-11-19-13-24-19)16-5-9-18(10-6-16)23-12-20-14-25-20/h3-10,19-20H,11-14H2,1-2H3

SMILES string

CC(C)(c1ccc(OCC2CO2)cc1)c3ccc(OCC4CO4)cc3

form

viscous liquid

composition

Epoxide equivalent weight, 172-176

density

1.16 g/mL at 25 °C (lit.)

Quality Level

100

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Application

Bisphenol A diglycidyl ether has been used:
  • to study its effects on propiomelanocortin (POMC):enhanced green fluorescent protein (EGFP) expression in our transgenic fish
  • to study the curing behavior, kinetics of epoxy, polyamidoamine systems and the influence of the incorporation of Fe3O4 magnetic nanoparticles (MNPs)
  • as a thermosetting resin
  • to determine the optimum composition of the epoxy-polysiloxane blend
  • for the preparation of transparent epoxy-based nanocomposite coatings
  • for the preparation, coating and curing of epoxy-graphene (E/G)

Biochem/physiol Actions

PPARγ inhibitor that blocks rosiglitazone- and insulin-induced adipogenesis.

Features and Benefits

This compound is featured on the Nuclear Receptors (PPARs) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

General description

Bisphenol A diglycidyl ether is an epoxy resin.

Other Notes

Epoxy resin often used in conjunction with DER 732 to form blocks of varying strength and hardness.

Legal Information

D.E.R. is a trademark of The Dow Chemical Company or an affiliated company of Dow

pictograms

Exclamation markEnvironment
GHS07,GHS09

signalword

Warning

Hazard Classifications

Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1

Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

507.2 - 514.4 °F - closed cup

flash_point_c

264 - 268 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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Certificates of Analysis (COA)

Lot/Batch Number
MKCX9992
MKCV5235
MKCW6886
MKCW2499
MKCT5598

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Enhanced Charpy impact strength of epoxy resin modified with vinyl-terminated polydimethylsiloxane
Vilcakova J, et al.
Journal of Applied Polymer Science, 135(4), 45720-45720 (2018)
Design and Manufacture of Textile Composites (2005)
Hoa H Le et al.
Endocrinology, 151(12), 5689-5699 (2010-10-12)
Estrogenic endocrine disrupting chemicals (EDCs) constitute a diverse group of man-made chemicals and natural compounds derived from plants and microbial metabolism. Estrogen-like actions are mediated via the nuclear hormone receptor activity of estrogen receptor (ER)α and ERβ and rapid regulation
Calorimetric analysis and molecular dynamics simulation of cure kinetics of epoxy/chitosan-modified Fe3O4 nanocomposites
Saeb MR, et al.
Progress in Organic Coatings, 112, 176-186 (2017)
Cure kinetics of epoxy/beta-cyclodextrin-functionalized Fe3O4 nanocomposites: experimental analysis, mathematical modeling, and molecular dynamics simulation
Saeb MR, et al.
Progress in Organic Coatings, 110, 172-181 (2017)
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