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D3132

Sigma-Aldrich

Silver diethyldithiocarbamate

Synonym(s):

DETC, Diethyldithiocarbamic acid silver salt

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About This Item

Linear Formula:
(C2H5)2NCSSAg
CAS Number:
1470-61-7
Molecular Weight:
256.14
Beilstein:
3718150
EC Number:
216-003-7
MDL number:
MFCD00004929
UNSPSC Code:
12171500
PubChem Substance ID:
57654088
NACRES:
NA.47

form

powder

Quality Level

200

mp

172-175 °C (lit.)

solubility

pyridine: 25 mg/mL, clear, yellow

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

2-8°C

SMILES string

CCN(CC)C(=S)S[Ag]

InChI

1S/C5H11NS2.Ag/c1-3-6(4-2)5(7)8;/h3-4H2,1-2H3,(H,7,8);/q;+1/p-1

InChI key

NSVHDIYWJVLAGH-UHFFFAOYSA-M

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Application

Spin trap used in conjunction with Fe2+ to detect NO in brain, kidney, liver, and other tissues. Simultaneous direct measurement of NO* and pO2 has been reported. A copper chelator, it has been used to quantitate copper in biological materials by ESR and is an inhibitor of superoxide dismutase, ascorbate oxidase, and other enzymes.
Also used for colorimetric determination of small quantities of arsenic.
Silver diethyldithiocarbamate has been used in cell culture.
Also used for colorimetric determination of small quantities of arsenic
Spin trap used in conjunction with Fe2+ to detect NO in brain, kidney, liver, and other tissues. Simultaneous direct measurement of NO* and pO2 has been reported. A copper chelator, it has been used to quantitate copper in biological materials by ESR and is an inhibitor of superoxide dismutase, ascorbate oxidase, and other enzymes.

Biochem/physiol Actions

Inhibits induction of macrophage nitric oxide synthase.
Silver diethyldithiocarbamate (AgDDC) is used to estimate the level of arsenic in human.
Inhibits induction of macrophage nitric oxide synthase.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Determination of the level of arsenic in human bodies (population of Basle).
Baumler J, et al.
International Journal of Legal Medicine, 64(2), 56-61 (1968)
Induction of the Expressions of Antioxidant Enzymes by Luteinizing Hormone in the Bovine Corpus Luteum.
Kawaguchi S, et al.
Journal of Reproduction and Development, 59(3), 219-224 (2013)
D Brune et al.
Swedish dental journal, 4(3), 125-128 (1980-01-01)
The reliability of the method for analysis for arsenic in dental cements according to the international standard ISO 2590 has been reinvestigated using nuclear tracer techniques and intercomparison of results obtained for the arsenic content of various cements by means
Sanjoy K Maji et al.
Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering, 42(7), 989-996 (2007-06-15)
The efficiency of a locally available laterite soil in removing both arsenite and arsenate from aqueous medium by adsorption was evaluated. It was observed that in batch experiment conducted at 0.5 mg/L initial concentration of arsenic, laterite soil could remove
Seth H Frisbie et al.
Environmental health perspectives, 113(9), 1196-1204 (2005-09-06)
All of Bangladesh's approximately 10 million drinking-water tube wells must be periodically tested for arsenic. The magnitude of this task and the limited resources of Bangladesh have led to the use of low-cost, semiquantitative field kits that measure As to
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