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Merck
CN

D2631

Dihexadecyl phosphate

Synonym(s):

DHP, Dicetyl phosphate

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About This Item

Linear Formula:
[CH3(CH2)15O]2P(O)OH
CAS Number:
Molecular Weight:
546.85
UNSPSC Code:
51191904
NACRES:
NA.25
PubChem Substance ID:
EC Number:
218-594-7
Beilstein/REAXYS Number:
1717117
MDL number:
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InChI key

RNPXCFINMKSQPQ-UHFFFAOYSA-N

InChI

1S/C32H67O4P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-35-37(33,34)36-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h3-32H2,1-2H3,(H,33,34)

SMILES string

OP(OCCCCCCCCCCCCCCCC)(OCCCCCCCCCCCCCCCC)=O

description

anionic

form

powder

mol wt

546.85 g/mol

technique(s)

DNA extraction: suitable

mp

74-75 °C (lit.)

lipid type

phospholipids

storage temp.

−20°C

Quality Level

Biochem/physiol Actions

Dihexadecyl phosphate (DHP) is a negatively charged lipid that is used for the formation of model membranes.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Susruta Samanta et al.
ACS infectious diseases, 4(10), 1519-1528 (2018-07-25)
Understanding molecular properties of outer membrane channels of Gram-negative bacteria is of fundamental significance as they are the entry point of polar antibiotics into bacteria. Outer membrane proteomics revealed OccK8 (OprE) to be among the five most expressed substrate specific
Hamdy Abdelkader et al.
Journal of pharmaceutical sciences, 100(5), 1833-1846 (2011-01-20)
This study aimed at preparing and evaluating Span 60-based niosomes for ocular delivery of naltrexone hydrochloride (NTX). Selected charged lipids [dicetyl phosphate (DCP) and stearyl amine (STA)] and surfactants [poly-24-oxyethylene cholesteryl ether (C24) and sodium cholate (CH)] were investigated as
Haruyuki Ishii et al.
Colloids and surfaces. B, Biointerfaces, 92, 372-376 (2011-12-16)
Hollow silica particle was obtained with a vesicle template synthesis in water under ambient conditions in the presence of ammonia. Biomimetic vesicles, liposomes were used, which consisted of a zwitterionic phospholipid, 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC), and a tiny amount of charged amphiphiles
Ba Hieu Tran et al.
International journal of nanomedicine, 14, 10061-10077 (2020-01-11)
S-propargyl-cysteine (SPRC; alternatively known as ZYZ-802) is a novel modulator of endogenous tissue H2S concentrations with known cardioprotective and anti-inflammatory effects. However, its rapid metabolism and excretion have limited its clinical application. To overcome these issues, we have developed some
Smita Pawar et al.
Journal of drug targeting, 24(8), 730-743 (2016-02-16)
Efficacy of anticancer drug is limited due to non-selectivity and toxicities allied with the drug; therefore the heart of the present work is to formulate drug delivery systems targeted selectively towards cancer cells with minimal toxicity to normal cells. Targeted

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