D1564
Anti-DR6 antibody produced in rabbit
IgG fraction of antiserum, buffered aqueous solution
Synonym(s):
Anti-Death Receptor 6
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About This Item
MDL number:
UNSPSC Code:
12352203
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biological source
rabbit
conjugate
unconjugated
antibody form
IgG fraction of antiserum
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 68 kDa
species reactivity
human
technique(s)
microarray: suitable
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
Gene Information
human ... TNFRSF21(27242)
General description
DR6 is a type I transmembrane receptor and possesses four extracellular cysteine-rich motifs and a cytoplasmic death domain. It is expressed in most human tissues and its expression is found to be increased in heart, brain, placenta, pancreas, thymus, lymph node and several non-lymphoid cancer cell lines.
Immunogen
synthetic peptide corresponding to amino acids 42-56 of the N-terminal region of human DR6 precursor.
Physical form
Solution in 0.01 M phosphate buffered saline containing 0.02% sodium azide.
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Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Identification and functional characterization of DR6, a novel death domain-containing TNF receptor.
G Pan et al.
FEBS letters, 431(3), 351-356 (1998-08-26)
Tumor nectosis factor (TNF) receptors are key players in inflammation and immune regulation. A new member of this family, termed death receptor-6 (DR6), has been identified. Like other death receptors, DR6 is a type I transmembrane receptor, possesses four extracellular
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