D1507
L-3,4-Dihydroxyphenylalanine methyl ester hydrochloride
solid
Sign Into View Organizational & Contract Pricing
All Photos(4)
Methyl L-DOPA hydrochloride
C10H13NO4 · HCl
Recommended Products
form
solid
Quality Level
color
white to off-white
storage temp.
−20°C
SMILES string
Cl[H].COC(=O)[C@@H](N)Cc1ccc(O)c(O)c1
InChI
1S/C10H13NO4.ClH/c1-15-10(14)7(11)4-6-2-3-8(12)9(13)5-6;/h2-3,5,7,12-13H,4,11H2,1H3;1H/t7-;/m0./s1
InChI key
WFGNJLMSYIJWII-FJXQXJEOSA-N
Application
L-3,4-Dihydroxyphenylalanine methyl ester hydrochloride has been used:
- in treating 6-hydroxydopamine induced lesions mice serotonin neurons
- in tyrosinase activity in B16F10 skin melanoma cells
- to test its neuroprotective effect in mesencephalic neurons
Biochem/physiol Actions
L-3,4-Dihydroxyphenylalanine methyl ester is a precursor to L-DOPA that crosses the blood-brain barrier. Antiparkinsonian agent L-DOPA methyl ester elicits antitumor functionality in leukemia and melanoma.
Caution
Light sensitive
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Intranasal administration of the dopaminergic agonists L-DOPA, amphetamine, and cocaine increases dopamine activity in the neostriatum: a microdialysis study in the rat
Journal of Neurochemistry, 68(1), 233-239 (1997)
Sodium tanshinone IIA silate increases melanin synthesis by activating the MAPK and PKA pathways and protects melanocytes from H2 O2-induced oxidative stress
Royal Society of Chemistry Advances, 9(33), 18747-18757 (2019)
Movement disorders : official journal of the Movement Disorder Society, 25(12), 1881-1887 (2010-07-30)
Melevodopa hydrochloride plus carbidopa in effervescent tablets (M/C) is a readily soluble antiparkinsonian tablet formulation. A total of 221 patients with Parkinson's disease and motor fluctuations entered a randomized, double-blind, double-dummy, controlled parallel group study, which compared the effectiveness of
3-O-Methyldopa inhibits astrocyte-mediated dopaminergic neuroprotective effects of l-DOPA
BMC Neuroscience, 17(1), 52-52 (2016)
L-Dopa methyl ester as a new antitumour agent
Nature, 269(5628), 512-513 (1977)
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service