Skip to Content

Dear Customer:

The current international situation is complex and volatile, and uncertain tariff policies may potentially impact our product prices. Given these uncertainties, we value your understanding regarding order-related matters.

If you decide to place an order during this period, we reserve the right to adjust the price based on the evolving situation. We understand that market changes may cause inconvenience. We will negotiate with you if there’s a significant price fluctuation due to tariff policy changes before the order’s actual delivery, and in such cases we may adjust or cancel the order as necessary.

For important updates on recent policy changes, please click here for more details.

Merck
CN
All Photos(3)

Key Documents

View All Documentation

D1411

Sigma-Aldrich

d-Desthiobiotin

≥98% (TLC)

Synonym(s):

5-Methyl-2-oxo-4-imidazolidinehexanoic acid

Sign Into View Organizational & Contract Pricing

Select a Size

500 MG
CN¥1,999.44
1 G
CN¥3,469.67

CN¥1,999.44

Available to ship onApril 17, 2025Details

Request a Bulk Order
All Photos(3)

Select a Size

Change View
500 MG
CN¥1,999.44
1 G
CN¥3,469.67

About This Item

Empirical Formula (Hill Notation):
C10H18N2O3
CAS Number:
533-48-2
Molecular Weight:
214.26
EC Number:
208-566-2
MDL number:
MFCD00213804
UNSPSC Code:
12352200
eCl@ss:
34058011
PubChem Substance ID:
24893431
NACRES:
NA.25

CN¥1,999.44

Available to ship onApril 17, 2025Details

Request a Bulk Order

Assay

≥98% (TLC)

form

powder

storage temp.

2-8°C

SMILES string

C[C@@H]1NC(=O)N[C@@H]1CCCCCC(O)=O

InChI

1S/C10H18N2O3/c1-7-8(12-10(15)11-7)5-3-2-4-6-9(13)14/h7-8H,2-6H2,1H3,(H,13,14)(H2,11,12,15)/t7-,8+/m0/s1

InChI key

AUTOLBMXDDTRRT-JGVFFNPUSA-N

Related Categories

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
A5575SML1915668095
d-Desthiobiotin ≥98% (TLC)

D1411

d-Desthiobiotin

Methyl δ-aminolevulinate hydrochloride ≥98% (TLC)

A5575

Methyl δ-aminolevulinate hydrochloride

T-26c ≥98% (HPLC)

SML1915

T-26c

4-(4-Bromothiophen-2-yl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid ethyl ester 98%

668095

4-(4-Bromothiophen-2-yl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid ethyl ester

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

-

form

powder

form

powder

form

powder

form

solid

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

Application

d-Desthiobiotin has been used as a component of elution buffers:
  • to elute the precipitated proteins from the resin during coimmunoprecipitation[1]
  • to elute human Cdc45–MCM–GINS (CMG) helicase during chromatographic protein purification[2]
  • to elute the heterodimeric kinesin family member 3A/B (KIF3A/B) and kinesin associated protein 3 (KAP3)-binding APC armadillo (APCARM) domain during chromatographic purification[3]

d-Desthiobiotin is used in affinity chromatography and protein chromatography. d-Desthiobiotin can be used for protein labeling, detection and isolation.

Biochem/physiol Actions

Desthiobiotin is a non-sulfur containing biotin derivative that binds less strongly to biotin-binding proteins and is easily dislocated by biotin.[4]

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves
  • Specification Sheet

    • Choose from one of the most recent versions:

    Certificates of Analysis (COA)

    Lot/Batch Number
    0000431809
    0000431809
    0000406415
    0000377607
    0000371984

    Don't see the Right Version?

    If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

    Search for a COA

    Already Own This Product?

    Find documentation for the products that you have recently purchased in the Document Library.

    Visit the Document Library

    Akihiko Sakamoto et al.
    Journal of bioscience and bioengineering, 105(3), 238-242 (2008-04-10)
    Fluorescence labeling of a cytokine at a specific site is required for observing cytokine-receptor interactions in living cells at the single-molecule level. Here, we demonstrated the C-terminus-specific fluorescence labeling of histidine-tagged thrombopoietin (TPO), a ligand for Mpl, with desthiobiotin-tagged fluorescent
    A Selective Chemical Probe for Coenzyme-A Requiring Enzymes.
    Hwang, Y., et al.
    Angewandte Chemie (International Edition in English), 119(40), 7765-7768 (2007)
    S Voss et al.
    Protein engineering, 10(8), 975-982 (1997-08-01)
    The Strep-tag, an artificial peptide ligand of streptavidin, has gained use as an affinity handle for the purification and detection of recombinant fusion proteins. In an attempt to achieve tighter complexation of the peptide, streptavidin was engineered and the amino
    Sudha Purushothaman et al.
    PloS one, 3(5), e2320-e2320 (2008-05-30)
    Fatty acids are indispensable constituents of mycolic acids that impart toughness & permeability barrier to the cell envelope of M. tuberculosis. Biotin is an essential co-factor for acetyl-CoA carboxylase (ACC) the enzyme involved in the synthesis of malonyl-CoA, a committed
    M Sárdy et al.
    Clinical chemistry, 45(12), 2142-2149 (1999-12-10)
    Tissue transglutaminase (TGc) has recently been identified as the major, if not the sole, autoantigen of gluten-sensitive enteropathy (GSE). We developed and validated an ELISA based on the human recombinant antigen and compared it to existing serological tests for GSE
    View All Related Papers

    Related Content

    Protein Research Guide

    Find protein research tools to prepare, isolate, and analyze proteins. Organized by how to extract, protect, purify, enrich, modify, and quantify proteins.

    Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

    Contact Technical Service