Skip to Content
Merck
CN

D041

S(+)-Propylnorapomorphine hydrochloride

solid

Synonym(s):

S(+)-NPA hydrochloride, S(+)10,11-Dihydroxy-N-n-propylnoraporphine hydrochloride

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C19H21NO2 · HCl
CAS Number:
79703-31-4
Molecular Weight:
331.84
NACRES:
NA.77
PubChem Substance ID:
24893232
UNSPSC Code:
12352210
MDL number:
MFCD00069246

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

InChI

1S/C19H21NO2.ClH/c1-2-9-20-10-8-12-4-3-5-14-17(12)15(20)11-13-6-7-16(21)19(22)18(13)14;/h3-7,15,21-22H,2,8-11H2,1H3;1H/t15-;/m0./s1

SMILES string

Cl.[H][C@@]12Cc3ccc(O)c(O)c3-c4cccc(CCN1CCC)c24

InChI key

PCOQOGIDTIFQAM-RSAXXLAASA-N

form

solid

color

off-white

solubility

H2O: moderately soluble, ethanol: soluble (Solutions should be freshly prepared.)

storage temp.

2-8°C

Quality Level

100

General description

Dissolve in oxygen-free boiled water containing 0.1% sodium metabisulfite or other antioxidant. Solutions should be freshly prepared.

Biochem/physiol Actions

Limbic-selective dopamine antagonist.

Disclaimer

Store tightly sealed at 4 °C; subject to rapid oxidation. Packed under argon; reseal bottle under argon or nitrogen to maximize stability.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H336

Hazard Classifications

STOT SE 3

target_organs

Central nervous system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

新产品
This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
033K4606

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

J L Neumeyer et al.
Journal of medicinal chemistry, 26(4), 516-521 (1983-04-01)
The enantiomers [(S)-(+) and (R)-(-)] of N-n-propylnorapomorphine (NPA) were synthesized. (R)-NPA was obtained by the acid-catalyzed rearrangement of N-n-propylnormorphine. (R)-NPA also was converted to (RS)-N-n-propylnorapomorphine dimethyl ether by dehydrogenation of the 10,11-O,O'-dimethyl ether of (R)-NPA with 10% palladium on carbon
R F Cox et al.
The Journal of pharmacology and experimental therapeutics, 247(1), 355-362 (1988-10-01)
Prompted by conflicting reports of both agonist and antagonist properties of the S-(+)-enantiomer of the potent dopamine agonist R-(-)-N-n-propylnorapomorphine (NPA), we carried out extracellular, single unit recording studies to compare the effects of both enantiomers on substantia nigra and ventral

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service