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D0256

Sigma-Aldrich

Dulcitol

≥99% (GC)

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Synonym(s):
Dulcite, Galactitol
Empirical Formula (Hill Notation):
C6H14O6
CAS Number:
Molecular Weight:
182.17
Beilstein:
1721903
EC Number:
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:
NACRES:
NA.25

Quality Level

Assay

≥99% (GC)

form

crystals

sweetness

<0.6 × sucrose

color

white

solubility

water: 50 mg/mL, clear, colorless

SMILES string

OC[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)CO

InChI

1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4+,5+,6-

InChI key

FBPFZTCFMRRESA-GUCUJZIJSA-N

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Application

Dulcitol (Galactitol), a sugar alcohol derived through reduction of galactose, is important in studies related to cataract formation, hepatosplenomegaly and mental retardation. It is used as a substrate to identify, differentiate and characterize galactitol dehydrogenase(s). Galactitol may be used as a reference compound in analytical procedures developed to analyze sugar alcohols in plants and food.

Biochem/physiol Actions

A sugar alcohol and slightly sweet tastant for human taste cells.

Other Notes

To gain a comprehensive understanding of our extensive range of Sugar alcohols for your research, we encourage you to visit our Carbohydrates Category page.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Lukas Müller et al.
Materials (Basel, Switzerland), 13(20) (2020-10-15)
Measuring thermo-physical properties of phase change materials (PCM) in a consistent and reliable manner is essential for system layout of thermal energy storages and correspondingly material selection. Only if basic properties are assessed in a comparable way a selection process
C Jakobs et al.
Pediatric research, 18(8), 714-718 (1984-08-01)
A stable isotope dilution assay for galactitol in amniotic fluid has been developed using selected ion monitoring chemical ionization gas chromatography-mass spectrometry of the hexaacetate derivative. [1,1-2H2]Galactitol was synthesized for use as the internal standard. Galactitol is a component of
Ignasi Barba et al.
Investigative ophthalmology & visual science, 51(9), 4416-4421 (2010-04-09)
To explore the metabolic profile of vitreous fluid of patients with proliferative diabetic retinopathy (PDR) using 1H-NMR-based metabonomic analysis. 1H-NMR spectra were acquired from vitreous samples obtained during vitrectomy from 22 patients with type 1 diabetes with PDR and from
G T Berry et al.
The Journal of pediatrics, 138(2), 260-262 (2001-02-15)
In a newborn infant with galactose-1-phosphate uridyltransferase deficiency and encephalopathy, brain magnetic resonance imaging revealed cytotoxic edema in white matter. Using in vivo proton magnetic resonance spectroscopy, we detected approximately 8 mmol galactitol per kilogram of brain tissue, an amount
Peter F Kador et al.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 25(4), 299-308 (2009-05-20)
The two most widely investigated animal models for diabetic retinopathy (DR) are the rat and dog. In dogs, aldose reductase (AR) is present only in retinal capillary pericytes and their destruction has been linked to polyol accumulation and resulting apoptosis.

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